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4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Purity >99.0% (HPLC) I-Almotriptan Aniline Precursor Factory Isithombe Esifakiwe
  • 4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Purity>99.0% (HPLC) I-Almotriptan Aniline Precursor Factory

4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Purity>99.0% (HPLC) I-Almotriptan Aniline Precursor Factory

Incazelo emfushane:

Igama: 4-[(1-Pyrrolidinylsulfonyl)methyl]aniline

I-CAS: 334981-10-1

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: Impushana Eyikristalu Ephuzi ukuya Ephuzi

I-Intermediate ye-Almotriptan Malate (CAS: 181183-52-8)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Almotriptan Malate Intermediates:
I-Almotriptan Malate CAS 181183-52-8
I-1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
I-4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9

Chemical Properties:

Igama Lekhemikhali 4- [(1-Pyrrolidinylsulfonyl)methyl]aniline
Omqondofana 1-[(4-Aminobenzyl)sulfonyl]pyrrolidine;I-Almotriptan Aniline Precursor
Inombolo ye-CAS 334981-10-1
Inombolo yeCAT I-RF-PI1948
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C11H16N2O2S
Isisindo samangqamuzana 240.32
I-Melting Point 170.0 ukuze 176.0 ℃
Ukuminyana 1.31
Ukuncibilika Incibilika Kancane ku-Toluene
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Eyikristalu Ephuzi ukuya Ephuzi
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (HPLC)
Ukulahlekelwa Ekumisweni <0.50%
Izinsalela ekushiseni <0.50%
Ukungcola Okukodwa Okukhulu <0.50%
Ukungcola Okuphelele <1.00%
Izinsimbi Ezisindayo <20ppm
I-Infrared Spectrum Ivumelana Nesakhiwo
I-NMR Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Almotriptan Aniline Precursor

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-4--[(1-Pyrrolidinylsulfonyl) methyl]aniline (CAS: 334981-10-1) iphakathi ekulungiseleleni i-Almotriptan Malate (CAS: 181183-52-8), i-Almotriptan Aniline Precursor.I-Almotriptan Malate iwuhlobo lomuthi we-triptan ongasetshenziswa ekwelapheni ubuhlungu bekhanda elibuhlungu.I-Almotriptan iyingxenye yezidakamizwa ezikhethiwe ze-serotonin receptor agonists.I-Almotriptan inobudlelwane obuphezulu nokucacile be-serotonin 5-HT receptors, okuholela phambili ekuvinjweni kwe-vascoconstriction yomkhumbi wegazi lobuchopho futhi kuthinte ukwabiwa kabusha kokugeleza kwegazi.Le miphumela imisa izimpawu zobuhlungu ukuthi zingathunyelwa ebuchosheni, futhi iqhubeke icindezela ukukhululwa kwezinto ezithile zemvelo ezibangela ubuhlungu, isicanucanu nezinye izimpawu ze-migraine.Kodwa-ke, i-Almotriptan ayikuvimbi ukuhlaselwa yi-migraine.I-Almotriptan, imakethwa ngo-2000, ine-oralbioavailability ephezulu kakhulu phakathi kwawo wonke ama-triptan.I-Almotriptan yenziwa i-metabolized yi-MAO-A ne-CYP3A4, ngakho-ke inephrofayili yemiphumela emihle kakhulu uma iqhathaniswa ne-Sumatriptan.

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