4-(4-Pyridinyl)thiazole-2-thiol CAS 77168-63-9 Purity ≥99.0% Ceftaroline Fosamil Cephalosporin Intermediate
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali: 4-(4-Pyridinyl)thiazole-2-thiol
I-CAS: 77168-63-9
Igama Lekhemikhali | 4-(4-Pyridinyl)thiazole-2-thiol |
Inombolo ye-CAS | 77168-63-9 |
Inombolo yeCAT | I-RF-PI558 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C8H6N2S2 |
Isisindo samangqamuzana | 194.28 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Okumhlophe Okumhlophe kuya Kuphuphu Ophuzi Okuphaphathekile |
Isivivinyo | ≥99.0% |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Izinto Ezihlobene | |
I-Single Max.Ukungcola | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Ceftaroline Fosamil (TAK-599), i-Cephalosporin derivative |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-4-(4-Pyridinyl) thiazole-2-thiol (CAS: 77168-63-9) isetshenziswa njengendawo ephakathi ye-Ceftaroline Fosamil (TAK-599).I-Ceftaroline Fosamil iyi-ejenti elwa namagciwane ye-cephalosporin eyavunywa e-United States ngo-Okthoba 2010 ekwelapheni kwe-IV kwezifo eziyingozi ze-bacterial skin and skin structure (ABSSSI) kanye nenyumoniya yebhaktheriya etholwe ngumphakathi (CABP).I-Ceftaroline Fosamil iwuketshezi oluncibilikayo emanzini, i-N-phosphono ye-ceftaroline (T-91825), i-spectrum ebanzi, i-ejenti ebulala amagciwane enomsebenzi onamandla ngokumelene nezinhlobo ze-Staphylococcus aureus (MRSA) ezimelana ne-methicillin, i-S. pneumonia engazweli emithini eminingi, kanye negremu evamile -izinto ezingezinhle.I-Ceftaroline ibophezela ku-PBP2a kanye namanye ama-PBP anobudlelwane obuphezulu futhi, ngenxa yalokho, igcina umsebenzi onamandla.I-Ceftaroline ibonisa umsebenzi omelene namagciwane amaningi e-gram-positive, okuhlanganisa i-β-lactam-susceptible and -resistant S. aureus, i-vancomycin-resistant S. aureus, kanye nezinhlobo ezikwazi ukumelana nezifo ze-S. pneumoniae kodwa inomsebenzi obuthakathaka ngokumelene ne-Enterococcus sp.Umsebenzi we-antibacterial we-gram-negative we-ceftaroline ulinganiselwe ikakhulukazi kumagciwane okuphefumula anjenge-Moraxella catarrhalis kanye ne-Haemophilus influenzae.