I-4-Amino-2-Methylbenzoic Acid CAS 2486-75-1 I-Tolvaptan Intermediate Factory
Ukunikezwa Komkhiqizi, Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo
I-Tolvaptan kanye Nezixhumanisi Ezihlobene:
I-Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
I-4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
I-2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Igama Lekhemikhali | I-4-Amino-2-Methylbenzoic Acid |
| Omqondofana | 4-Amino-o-toluic Acid;I-Tolvaptan Intermediate N-2 |
| Inombolo ye-CAS | 2486-75-1 |
| Inombolo yeCAT | I-RF-PI394 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | C8H9NO2 |
| Isisindo samangqamuzana | 151.17 |
| Ukuncibilika | I-Soluble ku-Methanol |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystal Powder Emhlophe noma Ephuzi |
| Ukuhlanzeka/Ukuhlaziya Indlela | ≥99.0% (HPLC) |
| Umswakama | ≤0.50% (KF) |
| I-Melting Point | 161.0 ~ 168.0℃ |
| Izinsalela ekushiseni | ≤0.50% |
| Ukungcola Okukodwa | ≤0.50% |
| Ukungcola Okuphelele | ≤1.0% |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Intermediate of Tolvaptan (CAS 150683-30-0), ukwelashwa kwe-Hyponatremia |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-4-Amino-2-Methylbenzoic Acid (i-CAS 2486-75-1) isetshenziswa njengendawo ephakathi ekuhlanganisweni kwemithi ephakathi kwemithi kanye ne-Active Pharmaceutical Ingredient (API) synthesis.I-4-Amino-2-Methylbenzoic Acid iphakathi kwe-Tolvaptan (CAS 150683-30-0).I-Tolvaptan ingumphikisi we-vasopressin okhethwa ngomlomo owakhiwe ngu-Otsuka ukuze elaphe i-hyponatremia, futhi iyi-non-peptide ekhetha i-antidiuretic hormone receptor antagonist.Umuthi ungakhuphula ukugcwala kwe-sodium ion ku-plasma, futhi usize ukuphuma kwamanzi ngokweqile emchameni.Umuthi ungathuthukisa ikhono lezinso lokubhekana namanzi, futhi wehlise kakhulu isisindo kanye ne-edema yeziguli kuyilapho ungahambisane nokukhushulwa kwe-electrolyte, ngaphandle kokulimaza ibhalansi ye-electrolyte yegazi.Umuthi ungasetshenziswa ekwelapheni i-hyponatremia ebangelwa ukuhluleka kwenhliziyo eqinile, izifo ezihlukahlukene ze-edema, i-cirrhosis kanye ne-antidiuretic hormone deficiency syndrome.
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