4-Amino-3-Chlorophenol CAS 17609-80-2 Lenvatinib Mesylate Intermediate Purity >99.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: 4-Amino-3-Chlorophenol

I-CAS: 17609-80-2

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: I-Brown Solid Powder

I-Intermediate ye-Lenvatinib Mesylate CAS 857890-39-2

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali 4-Amino-3-Chlorophenol
Omqondofana 3-Chloro-4-Aminophenol;Lenvaint-G
Inombolo ye-CAS 17609-80-2
Inombolo yeCAT I-RF-PI1968
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C6H6ClNO
Isisindo samangqamuzana 143.57
Ukuminyana 1.406±0.060 g/cm3
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka I-Brown Solid Powder
1 H NMR Spectrum Ihambisana Nesakhiwo
Identification-HPLC Isikhathi sokugcina sifana nejwayelekile
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (HPLC)
I-Melting Point 138.0~141.0℃
Ukulahlekelwa Ekumisweni <1.00%
Izinsalela ekushiseni <0.30%
Ukungcola Okuphelele <1.00%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate ye-Lenvatinib Mesylate (CAS: 857890-39-2)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-4-Amino-3-Chlorophenol (i-CAS: 17609-80-2) iyindawo ebalulekile yemithi, esetshenziswa kabanzi ekwakhiweni nasekuhlanganiseni kwe-anti-tumor, izifo zenhliziyo, izifo ze-neurological.I-4-Amino-3-Chlorophenol iyingxenye ebalulekile yokulungiswa kwe-Lenvatinib Mesylate (CAS: 857890-39-2).Ithuthukiswe ngabakwa-Eisai Inc., i-lenvatinib mesylate iyi-vascular endothelial growth factor receptor (VEGF) inhibitor enomsebenzi omelene ne-VEGF subtypes 1, 2, no-3 futhi yagunyazwa yi-FDA ngo-2015 ukuze zelashwe umdlavuza wegilo ohlukile otholakala endaweni. ukuphindaphinda, i-metastatic, noma ukuqhubeka futhi ayizange iphendule ekwelashweni kwe-iodine enemisebe.NgoMeyi 2016, i-FDA yagunyaza umuthi njengendlela yokwelapha eyinhlanganisela ne-everolimus yokwelapha i-advanced renal cell carcinoma.Ngenxa yokuthi i-VEGF (kanye ne-fibroblast growth factor receptors, eyaziwa ngokuthi ama-FGFR) kucatshangwa ukuthi idlala indima emizileni yokubonisa izimpawu zenhliziyo, ukuvimbela i-VEGF2R kanye ne-FGFR kucatshangwa ukuthi yizinqubo ezingemuva komphumela oyinhloko we-lenvatinib mesylate, okuwumfutho wegazi ophezulu.

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