I-4-Aminosalicylic Acid CAS 65-49-6 Ukuhlanzeka >99.0% (HPLC) (T) Factory

Incazelo emfushane:

Igama Lekhemikhali: 4-Aminosalicylic Acid

Synonyms: 4-Amino-2-Hydroxybenzoic Acid;4-ASA;I-PAS

CAS: 65-49-6

Ubumsulwa: >99.0% (HPLC) (T)

Ukubukeka: Impushana Emhlophe-Emhlophe noma Ephuzi Kancane

USP Standard, Commercial Production

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Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-4-Aminosalicylic Acid (CAS: 65-49-6) enekhwalithi ephezulu.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo kulo mkhiqizo, sicela uthumele imininingwane enemininingwane ehlanganisa inombolo ye-CAS, igama lomkhiqizo, nenani kithi.Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali 4-Aminosalicylic Acid
Omqondofana I-4-Amino-2-Hydroxybenzoic Acid;I-4-Amino-Salicylic Acid;4-ASA;I-PAS;I-Para-aminosalicylic acid;i-p-aminosalicylic acid;i-aminosalicylic acid;Amino-PAS;4-Aminosalicylate
Ukungcola I-Mesalazine EP Ukungcola E
Inombolo ye-CAS 65-49-6
Inombolo yeCAT RF2746
Isimo Sesitoko Esitokweni, Amandla Okukhiqiza Amathani angama-30 ngenyanga
I-Molecular Formula C7H7NO3
Isisindo samangqamuzana 153.14
I-Melting Point 135.0~145.0℃(lit.)
Kuyazwela I-Hygroscopic.Izwela Ukukhanya, Izwela Umoya
I-Solubility ku-Methanol Cishe Ukungafihli
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Engamhlophe noma Ephuzi Kancane
Ukuhlonza Qalisa Ukusabela Okuhle
Ukucaca kanye Nombala Wesixazululo Iyahambisana
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (HPLC)
Ukuhlanzeka / Indlela Yokuhlaziya 98.5~101.5% (Titration by NaOH)
I-Melting Point 135.0~145.0℃
Ukulahlekelwa Ekumisweni <0.50%
Izinsalela ekushiseni <0.20%
I-Chloride (Cl) <0.042%
Izinsimbi Ezisindayo <30ppm
Okuqukethwe kwe-m-Aminophenol <0.25% (HPLC)
I-Hydrogen Sulfide, Sulfur Dioxide ne-Amyl Alcohol Iyahambisana
Ukungcola Okuphelele <1.00%
pH 3.0~3.7
I-Infrared Spectrum Ivumelana Nesakhiwo
I-Proton NMR Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola Lo Mkhiqizo Ngokuhlola Uvumelana Ne-USP30 Ejwayelekile
Ukusetshenziswa Pharmaceutical Intermediates

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Isicelo:

I-4-Aminosalicylic Acid (4-ASA) (CAS: 65-49-6), i-aminobenzoic acid eyi-salicylic acid efakwe endaweni yeqembu le-amino endaweni yesi-4, ingenye yezidakamizwa zokugcina ezisele ezitholakalayo zokwelapha ukumelana nezidakamizwa kakhulu ( XDR) isifo sofuba.Kuyi-antitubercular ejenti evamise ukulawulwa ngokuhlangana ne-Isoniazid.I-4-Aminosalicylic Acid ibonisa imisebenzi yokulwa nokuvuvukala, i-antioxidative, ne-antibacterial;isetshenziswa ngokomtholampilo ukwelapha isifo samathumbu esivuvukalayo (IBD), isifo sikaCrohn, kanye ne-colitis, njengoba isebenza ngokuyinhloko kukholoni.Ivamise ukuthathwa ngomlomo.I-4-Aminosalicylic Acid isetshenziswa ngokumelene ne-Mycobacterium njengokwelapha isifo sofuba;ivimbela umsebenzi we-dihydrofolate reductase (DHFR) njenge-antimetabolite.I-4-Aminosalicylic Acid, isidakamizwa se-antituberculosis, iyimodeli yesithako esisebenzayo semithi sokucwaninga ukwakheka kukasawoti kanye ne-cocrystal ku-molecule yokusebenza kwe-hydrogen-bonding ene-carboxylic acid, i-amine, namaqembu e-phenol.I-antibacterial ekwazi ukuvimbela ukukhula kwe-Mycobacterium tuberculosis.I-4-Aminosalicylic Acid ingasetshenziswa ekuhlanganiseni: I-Azo derivatives ye-4-ASA enemiphumela yokulwa nokuvuvukala;I-Ammonium 4-aminosalicylate kasawoti polymorphs esetshenziswa njengezithako zemithi;Ama-analogues e-salicylic acid-triazole asetshenziswa njenge-quorum sensing inhibitors ngokumelene ne-Pseudomonas aeruginosa.

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