I-5-Bromo-2-Chloro-4′-Ethoxydiphenylmethane CAS 461432-23-5 I-Dapagliflozin Intermediate Factory
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
I-Dapagliflozin (CAS: 461432-26-8) Izimaphakathi Ezihlobene:
I-5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
Igama Lekhemikhali | 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane |
Omqondofana | 4-Bromo-1-Chloro-2-(4-Ethoxybenzyl)benzene;4-(5-Brom-2-Chlorbenzyl)phenyl-Ethylether;I-Dapagliflozin Bromo Ukungcola |
Inombolo ye-CAS | 461432-23-5 |
Inombolo yeCAT | I-RF-PI447 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C15H14BrClO |
Isisindo samangqamuzana | 325.63 |
I-Melting Point | 41.0 ukuze 43.0℃ |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Ephuzi kuya Kumhlophe |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
Amanzi (KF) | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Dapagliflozin (CAS: 461432-26-8), uhlobo lwesifo sikashukela sohlobo II |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
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I-4-Bromo-1-Chloro-2-(4-Ethoxybenzyl)benzene (CAS: 461432-23-5) isetshenziswa njengendawo emaphakathi ekuhlanganisweni kwe-Dapagliflozin (CAS: 461432-26-8).I-Dapagliflozin iyi-inhibitor enamandla, ekhethiwe ye-glucose cotransporter 2 (SGLT2) encike ezinso ezinso ekwelapheni isifo sikashukela sohlobo 2.I-Dapagliflozin isidakamizwa esisha se-antidiabetic esakhiwe ngokuhlanganyela yi-Bristol-Myers Squibb kanye ne-AstraZeneca, sigunyazwe yi-European Medicines Agency (EMA) ngoNovemba 12, 2012. Ngomhla ziyisi-8 kuJanuwari, 2014, i-US Food and Drug Administration (FDA) ikugunyazile. ukuze isetshenziswe ekwelapheni isifo sikashukela sohlobo II.