I-Olaparib Intermediate CAS 763114-26-7 Purity ≥98.5% Factory
Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
I-Olaparib kanye Nezixhumanisi Ezihlobene:
I-Olaparib CAS 763113-22-0
I-2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid CAS 763114-26-7
1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8
I-3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
Igama Lekhemikhali | 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid |
Omqondofana | 2-Fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoic acid |
Inombolo ye-CAS | 763114-26-7 |
Inombolo yeCAT | I-RF-PI450 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C16H11FN2O3 |
Isisindo samangqamuzana | 298.27 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Ephuzi ukuya Emhlophe |
Isivivinyo | ≥98.5% |
Umswakama (KF) | ≤0.50% |
Ukungcola Okuphelele | ≤1.5% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate of Olaparib (CAS: 763113-22-0) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid (CAS: 763114-26-7) iyindawo ephakathi esetshenziswa ekuhlanganiseni kwe-Olaparib (CAS: 763113-22) -0).I-Olaparib, imakethwa yi-AstraZeneca ngaphansi kwegama lomkhiqizo i-Lynparza, yavunywa e-USA ngoDisemba 2014 njengendlela yokwelapha ehlosiwe, ene-ejenti eyodwa yokwelapha umdlavuza we-ovarian othuthukisiwe we-BRCA-mediated advanced ovarian. , isebenza njenge-poly ADP ribose polymerase inhibitor futhi igunyazwe ngokukhethekile ezigulini ezithole ukwelashwa okuthathu noma ngaphezulu kwe-chemotherapy.Ezivivinyweni zomtholampilo, isidakamizwa sandise ukusinda kokungaqhubeki isikhathi eside ezigulini ezinomdlavuza we-serous ovarian ophindelelayo ozwela i-platinum.I-Olaparib nayo okwamanje isezigabeni ezehlukene zophenyo ukuze zelashwe umdlavuza webele, wesisu, wendlala yesinye, we-pancreatic kanye nowokungewona omncane wamaphaphu.