I-4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Ubumsulwa >98.5% (HPLC) Isithombe Esifakiwe Sefektri Ephakathi ye-Lenvatinib Mesylate

I-4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Ubumsulwa >98.5% (HPLC) I-Lenvatinib Mesylate Intermediate Factory

Incazelo emfushane:

Igama: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

I-CAS: 417721-36-9

Ubumsulwa: >98.5% (HPLC)

Ukubukeka: Okumhlophe Okumhlophe ukuya Kokuphuzi Okukhanyayo

I-Intermediate ye-Lenvatinib Mesylate CAS 857890-39-2

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Lenvatinib Mesylate Intermediates With High Purity
I-Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
I-Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
I-Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
I-Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
I-4-Amino-3-Chlorophenol CAS 17609-80-2
I-4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
I-Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Chemical Properties:

Igama Lekhemikhali	4-Chloro-7-Methoxyquinoline-6-Carboxamide
Omqondofana	I-4-Chloro-7-Methoxy-6-Quinolinecarboxamide;I-Lenvatinib Ukungcola 12;I-Lenvatinib Ukungcola B;I-Lenvatinib Ukungcola LFS-B
Inombolo ye-CAS	417721-36-9
Inombolo yeCAT	I-RF-PI1971
Isimo Sesitoko	Esitokweni, Amandla Okukhiqiza 50MT/Ngonyaka
I-Molecular Formula	I-C11H9ClN2O2
Isisindo samangqamuzana	236.65
I-Melting Point	>205℃ (December)
Ukuminyana	1.380±0.060 g/cm3
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Off-White to Light Yellow Powder
Ukuhlanzeka / Indlela Yokuhlaziya	>98.5% (HPLC)
Ukulahlekelwa Ekumisweni	<0.50%
Izinsalela ekushiseni	<0.50%
Ukungcola Okuphelele	<1.50%
I-Proton NMR Spectrum	Ivumelana Nesakhiwo
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Intermediate ye-Lenvatinib Mesylate (CAS: 857890-39-2)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

Isicelo:

I-4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) isetshenziswa kakhulu njengendawo ephakathi ye-Lenvatinib Mesylate (CAS: 857890-39-2).Ithuthukiswe ngabakwa-Eisai Inc., i-lenvatinib mesylate iyi-vascular endothelial growth factor receptor (VEGF) inhibitor enomsebenzi omelene ne-VEGF subtypes 1, 2, no-3 futhi yagunyazwa yi-FDA ngo-2015 ukuze zelashwe umdlavuza wegilo ohlukile otholakala endaweni. ukuphindaphinda, i-metastatic, noma ukuqhubeka futhi ayizange iphendule ekwelashweni kwe-iodine enemisebe.NgoMeyi 2016, i-FDA yagunyaza umuthi njengendlela yokwelapha eyinhlanganisela ne-everolimus yokwelapha i-advanced renal cell carcinoma.Ngenxa yokuthi i-VEGF (kanye ne-fibroblast growth factor receptors, eyaziwa ngokuthi ama-FGFR) kucatshangwa ukuthi idlala indima emizileni yokubonisa izimpawu zenhliziyo, ukuvimbela i-VEGF2R kanye ne-FGFR kucatshangwa ukuthi yizinqubo ezingemuva komphumela oyinhloko we-lenvatinib mesylate, okuwumfutho wegazi ophezulu.