4-Chlorobenzo[b]thiophene CAS 66490-33-3 Purity >98.0% (GC) Brexpiprazole Intermediate Factory
I-Ruifu Chemical Supply Brexpiprazole Intermediates
I-Brexpiprazole CAS 913611-97-9
I-7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-one CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Igama Lekhemikhali | 4-Chlorobenzo[b]thiophene |
Omqondofana | 4-Chloro-Benzo[b]thiophene;4-Chloro-1-Benzothiophene;4-Chlorobenzothiophene |
Inombolo ye-CAS | 66490-33-3 |
Inombolo yeCAT | I-RF-PI1983 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C8H5ClS |
Isisindo samangqamuzana | 168.64 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Uketshezi Olungenambala |
Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (GC) |
Ukungcola Okuphelele | <2.00% |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
I-NMR | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Brexpiprazole (CAS: 913611-97-9) |
Iphakheji: Ibhodlela Elifakwe Fluorinated, 25kg/Drum, noma ngokwezidingo zekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-4-Chlorobenzo[b]thiophene (CAS: 66490-33-3) iyi-Intermediate ye-Brexpiprazole (CAS: 913611-97-9).I-Brexpiprazole iyinoveli yesidakamizwa se-antipsychotic esebenza njengemoduli yomsebenzi we-serotonin ® dopamine futhi ibonise ukusebenza kahle njengokwelashwa okungeziwe ezigulini ezinokuphazamiseka okukhulu kokucindezeleka (MDD).Isidakamizwa sibonisa iphrofayili ye-pharmacological eyingqayizivele, esebenza njenge-agonist ingxenye ye-serotonin 5-HT1A kanye ne-dopamine D2 receptors futhi njengomphikisi ogcwele we-5-HT2A kanye ne-noradrenaline α1B / 2C receptors, enobudlelwane obubophezelayo obufanayo be-subnanomolar.Umuthi, owakhiwa u-Otsuka kanye no-Lundbeck, wagunyazwa ngo-2015 yi-FDA ukuze welaphe i-schizophrenia kanye nokwelapha okuhlanganisa nokudangala.I-Brexpiprazole ibhekwa kabanzi njengelandela isidakamizwa se-antipsychotic sika-Otsuka i-aripiprazole (igama lokuhweba i-Abilify) ilungelo layo lobunikazi eliphelelwe yisikhathi ngo-Agasti 2014.