4-Chlorobenzo[b]thiophene CAS 66490-33-3 Purity >98.0% (GC) Brexpiprazole Intermediate Factory

Incazelo emfushane:

Igama Lekhemikhali: 4-Chlorobenzo[b]thiophene

I-CAS: 66490-33-3

Ubumsulwa: >98.0% (GC)

Ukubukeka: Uketshezi Olungenambala

I-Intermediate ye-Brexpiprazole (CAS: 913611-97-9)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali 4-Chlorobenzo[b]thiophene
Omqondofana 4-Chloro-Benzo[b]thiophene;4-Chloro-1-Benzothiophene;4-Chlorobenzothiophene
Inombolo ye-CAS 66490-33-3
Inombolo yeCAT I-RF-PI1983
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C8H5ClS
Isisindo samangqamuzana 168.64
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Uketshezi Olungenambala
Ukuhlanzeka / Indlela Yokuhlaziya >98.0% (GC)
Ukungcola Okuphelele <2.00%
I-Infrared Spectrum Ivumelana Nesakhiwo
I-NMR Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate ye-Brexpiprazole (CAS: 913611-97-9)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela Elifakwe Fluorinated, 25kg/Drum, noma ngokwezidingo zekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-4-Chlorobenzo[b]thiophene (CAS: 66490-33-3) iyi-Intermediate ye-Brexpiprazole (CAS: 913611-97-9).I-Brexpiprazole iyinoveli yesidakamizwa se-antipsychotic esebenza njengemoduli yomsebenzi we-serotonin ® dopamine futhi ibonise ukusebenza kahle njengokwelashwa okungeziwe ezigulini ezinokuphazamiseka okukhulu kokucindezeleka (MDD).Isidakamizwa sibonisa iphrofayili ye-pharmacological eyingqayizivele, esebenza njenge-agonist ingxenye ye-serotonin 5-HT1A kanye ne-dopamine D2 receptors futhi njengomphikisi ogcwele we-5-HT2A kanye ne-noradrenaline α1B / 2C receptors, enobudlelwane obubophezelayo obufanayo be-subnanomolar.Umuthi, owakhiwa u-Otsuka kanye no-Lundbeck, wagunyazwa ngo-2015 yi-FDA ukuze welaphe i-schizophrenia kanye nokwelapha okuhlanganisa nokudangala.I-Brexpiprazole ibhekwa kabanzi njengelandela isidakamizwa se-antipsychotic sika-Otsuka i-aripiprazole (igama lokuhweba i-Abilify) ilungelo layo lobunikazi eliphelelwe yisikhathi ngo-Agasti 2014.

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