I-4-Hydroxycoumarin CAS 1076-38-6 Ubumsulwa >99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-4-Hydroxycoumarin (CAS: 1076-38-6) enekhwalithi ephezulu.I-Ruifu Chemical ingahlinzeka ngokulethwa komhlaba wonke, amanani ancintisanayo, amanani amancane nayinqwaba atholakalayo.Thenga i-4-Hydroxycoumarin,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-4-Hydroxycoumarin |
| Omqondofana | I-4-Hydroxy-1-Benzopyran-2-one;4-Coumarinyl Utshwala;4-Coumarinol;4-Hydroxy-2H-Benzo[b]pyran-2-one;I-4-Hydroxy-2H-Chromen-2-one;4-Hydroxychromen-2-one;I-Benzotetronic Acid |
| Isimo Sesitoko | Esitokweni, Kwenzelwe Ukuthengisa |
| Inombolo ye-CAS | 1076-38-6 |
| I-Molecular Formula | C9H6O3 |
| Isisindo samangqamuzana | 162.14 g/mol |
| I-Melting Point | 213.0~217.0℃(lit.) |
| Ukuminyana | 1.446 |
| Ukuncibilika kwamanzi | Ayincibiliki Emanzini |
| Ukuncibilika | I-Soluble ku-Ethanol ne-Dimethyl Formamide |
| Isikhathi Sokugcina. | Indawo Epholile Neyomile |
| I-COA ne-MSDS | Iyatholakala |
| Isigaba | Pharmaceutical Intermediates |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | I-Crystalline Powder Emhlophe noma Cishe Emhlophe | Iyahambisana |
| I-Melting Point | 213.0~217.0℃ | 213.6 ~ 214.7℃ |
| Ukulahlekelwa Ekumisweni | <0.50% | 0.32% |
| Izinsalela ekushiseni | <0.20% | 0.08% |
| Izinsimbi Ezisindayo (Pb) | ≤10ppm | <10ppm |
| Ukungcola Okukodwa | <0.30% | Iyahambisana |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) | 99.64% |
| I-Infrared Spectrum | Ivumelana Nesakhiwo | Iyahambisana |
| 1 H NMR Spectrum | Ivumelana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nemibandela enikeziwe | |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina esitsheni esivalwe ngci.Gcina endaweni epholile, eyomile futhi enomoya omuhle.Vikela ekukhanyeni nakumswakama.Akuhambisani nama-oxidizing agents aqinile nezisekelo eziqinile.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
4 Indlela yokuhlola
4.1 Ukubukeka (ukuhlola okubonakalayo)
4.2 Ukulahlekelwa ngokomiswa
4.3 Ukunqunywa kokuqukethwe kwe-4-Hydroxycoumarin
4.3.1 Indlela yokunquma
Amasampuli ahlakazwe esigabeni samaselula futhi anqunywa ukusebenza okuphezulu kwe-chromatography ye-liquid kukholomu ye-C18 ngendlela ephakeme yendawo evamile.
4.3.2 I-Regent
a) I-acetonitrile: i-chromatographic pure (ingenisiwe);
b) Amanzi: Amanzi ahlanganisiwe noma amanzi acwecwe esibili.
4.3.3 Ithuluzi
a) Ukusebenza okuphezulu kwechromatography yoketshezi;
b) I-spectrometer ye-wavelength eguquguqukayo ye-UV;
c) Ikholomu yokuhlaziya: C18 ikholomu;
d) Ama-oscillator e-Ultrasonic.
4.3.4 Izimo zokusebenza zeChromatographic
a) Isigaba seselula: i-acetonitrile: amanzi: i-phosphoric acid = 700:300:1 (V/V/ V);
b) Izinga lokugeleza: 1.0ml/min;
c) Izinga lokushisa lekholomu: izinga lokushisa legumbi;
d) Ubude begagasi bokutholwa: 254nm
e) Usayizi wesampula: 20μL
4.3.5 Ukulungiswa kwesixazululo sokuhlola
Kala isampula engu-20mg (enembile ibe ngu-0.002g), uyibeke ebhodleleni le-volumetric engu-25ml, uyiqede ngesigaba seselula ku-4.2.4 a) esikalini, uyinyakazise kahle ku-shaker ye-ultrasonic ukuze isetshenziswe kamuva.
4.3.6 Ukunqunywa kokuqukethwe
Ngaphansi kwemibandela ye-4.3.4 ngenhla, isisombululo sokuhlola sizonqunywa ngemuva kokuthi ithuluzi lizinzile.
4.3.7 Ukubala
Indlela yokujwayela yendawo ephakemeyo isetshenziswe ukubala imiphumela.
4.3.8 Ukuchezuka okuvumelekile
Ukuchezuka kwezilinganiso ezimbili akukho ngaphezu kuka-0.5%, futhi inani elimaphakathi elibaliwe lithathwa njengomphumela wokuhlolwa.
4.4 Ukunqunywa kwendawo encibilikayo.
5 Imithetho Yokuhlola
5.1 Iqoqo ngalinye lemikhiqizo lizohlolwa umnyango wokuhlola ikhwalithi ngokuya ngezinto ezikuleli zinga ngaphambi kokuphuma embonini.
5.2 Ukunqunywa kwamaqoqo
Iqoqo lemikhiqizo ekhiqizwa ngenani lokudla (cishe ama-200kg).
5.3 Ukusampula
Izikhwama ezimbili (imiphongolo) zikhethwa ngokungahleliwe ephaketheni leqoqo ngalinye lemikhiqizo.Ngemuva kokuthatha amasampula nokuxuba ngokulinganayo, ahlukaniswa abe ngu-50g ngendlela yezingxenye ezine, ezihlukaniswe izingxenye ezimbili, enye yazo isetshenziselwa ukuhlolwa kanti enye igcinelwe ukubhekisela.
5.4 Isinqumo
Iqoqo ngalinye lemikhiqizo lizohlolwa ngokwezidingo ezibekwe kuleli zinga.Uma noma iyiphi into yehluleka ukuhlangabezana nezimfuneko ezibekwe kuleli zinga, izovunyelwa ukuthi iphinde ihlolwe ngamasampula aphindwe kabili.Uma kusekhona into eyodwa ehlulekayo ukuhlangabezana nezimfuneko ezibekwe kuleli zinga, iqoqo lemikhiqizo lizobhekwa njengelingafaneleki.
5.5 Ukulamula
Umsebenzisi unelungelo lokwenza ukuhlolwa kokwamukelwa phakathi kwezinsuku eziyi-15 ngemuva kokuthola izimpahla ngokuya ngezinhlinzeko zaleli zinga.Esimeni sanoma yikuphi ukuphikisa kwekhwalithi, zombili izinhlangothi zingaxoxisana ukuze zikuxazulule, noma zinikeze isikhungo sokulamula esisemthethweni okuvunyelwene ngazo zombili izinhlangothi ukuthi sibambe isixazululi ngokuvumelana nezinhlinzeko zaleli zinga.
6 Amalebula namalebula
Amamaki alandelayo azonamathiselwa ephaketheni lomkhiqizo:
a) Igama lomkhiqizo;
b) Inombolo ejwayelekile;
c) Isisindo esiphelele;
d) Usuku lokukhiqiza noma inombolo yeqoqo;
e) Igama nekheli lemboni;
f) Impilo yeshelufu.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Amakhodi Engozi
R22 - Iyingozi uma igwinywe
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yokuphepha
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
I-WGK Germany 3
I-RTECS DJ3100000
TSCA Yebo
I-HS Code 2932201000
I-Hazard Note Irritant
I-4-Hydroxycoumarin (i-CAS: 1076-38-6) iyi-hydroxycoumarin eyi-coumarin lapho i-hydrogen esendaweni yesi-4 ithathelwa indawo yiqembu le-hydroxy.I-conjugate acid ye-4-hydroxycoumarin (1-).
I-4-Hydroxycoumarin isitshalo esitholakala ku-antioxidant, esivikela ku-lipid peroxidation, kanye ne-inhibitor engaba khona ye-HIV-1 Integrase.I-4-Hydroxycoumarins iyisigaba esibaluleke kakhulu semithi esebenzayo ye-biologically esetshenziswa kakhulu njengama-anticoagulants-Warfarin ne-Acenocoumarol.
I-4-Hydroxycoumarin, i-coumarin derivative, ingenye ye-heterocyclic scaffolds eguquguqukayo futhi isetshenziswa kaningi ekuhlanganisweni kwezinhlanganisela ezihlukahlukene zezinto eziphilayo.I-4-Hydroxycoumarin inezinto zombili ze-electrophilic kanye ne-nucleophilic.I-4-Hydroxycoumarin derivatives isetshenziswa njenge-anticoagulant, antibacterial, antifungal, antiviral, antitumor, antiprotozoal, insecticidal, antimycobacterial, antimutagenic, antioxidant, anti-inflammatory agents, HIV protease inhibitors kanye ne-tyrosine kinase inhibitors.
I-4-Hydroxycoumarin ihileleke ekuphenduleni kokuchithwa, ngenxa ye-asidi ephezulu uma kuqhathaniswa yebhondi ye-CH endaweni engu-3: ukusabela kwezingxenye ezintathu nge-isocyanides kanye ne-dialkyl acetylene dicarboxylates inikeza ama-4H-pyrans aguquliwe.
I-4-Hydroxycoumarin iyimithi emaphakathi kanye nesibulala-zinambuzane.
I-4-Hydroxycoumarin nayo iyisinongo, futhi ama-coumarin asatshalaliswa kabanzi embusweni wezitshalo.
