4-(Methylsulfonyl)phenylacetic Acid CAS 90536-66-6 Purity >99.5% (HPLC) Etoricoxib Intermediate Factory
Umkhiqizi Oholayo Nomhlinzeki, Abamaphakathi be-Etoricoxib
I-Etoricoxib API CAS 202409-33-4
4-(Methylthio)Phenylacetic Acid CAS 16188-55-9
4-(Methylsulfonyl)Phenylacetic Acid CAS 90536-66-6
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Igama Lekhemikhali | 4-(Methylsulfonyl)phenylacetic Acid |
Omqondofana | 4-Methylsulphonylphenylacetic Acid;4-(Methanesulfonyl)phenylacetic Acid;(4-Methanesulfonylphenyl)i-acetic Acid;4-Methylsulfonyl Phenyl Acetic Acid;2-(4-(Methylsulfonyl)phenyl)i-acetic Acid;[p-(Methylsulfonyl)phenyl] -Acetic Acid;I-4-Mesylphenylacetic Acid |
Inombolo ye-CAS | 90536-66-6 |
Inombolo yeCAT | I-RF-PI1182 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C9H10O4S |
Isisindo samangqamuzana | 214.24 |
I-Melting Point | 136.0 ukuze 140.0 ℃ |
Ukuminyana | 1.35 |
Ukuncibilika | I-Soluble ku-Methanol |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Eqinile Emhlophe ukuya Kokumhlophe |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.5% (HPLC) |
I-Melting Point | 136.0 ukuze 140.0 ℃ |
Umswakama (KF) | <0.50% |
Ukungcola Okukodwa Okukhulu Kakhulu | <0.30% |
Ukungcola Okuphelele | <0.50% |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Etoricoxib (CAS: 202409-33-4) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
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I-4-(Methylsulfonyl)phenylacetic Acid (CAS: 90536-66-6) iphakathi kwe-Etoricoxib (CAS: 202409-33-4).I-Etoricoxib iwuhlobo lwe-cyclooxygenase-2 (COX-2) inhibitors olukhetha kakhulu olwakhiwe inkampani yakwaMerck.I-Etoricoxib isetshenziswa kabanzi ekwelapheni i-osteoarthritis (OA), i-rheumatoid arthritis, i-ankylosing spondylitis, izinhlungu ezingapheli emhlane, i-acute gouty arthritis, i-dysmenorrhea eyinhloko kanye nobuhlungu bangemva kokuhlinzwa, nezinye izifo.I-Etoricoxib, i-COX-2 inhibitor ekhethiwe, inemiphumela elwa nokuvuvukala, i-analgesic kanye ne-antipyretic, ifaneleka ukwelashwa kwezimpawu nezimpawu ze-osteoarthritis eyingozi futhi engapheli, kanye ne-acute gouty arthritis.I-Etoricoxib imuncwa ngokushesha, nge-bioavailability yomlomo engama-80 kuye ku-100%, futhi ifinyelela ekugxilweni okuphezulu kwe-plasma emahoreni angu-1 kuya kwangu-2 ngemva komthamo.Ukudla kwehlisa izinga lokumuncwa kodwa akunawo umthelela ezingeni lokumuncwa.Ibonisa isigamu sempilo ende yokuqeda cishe amahora angama-22, ikhombisa i-pharmacokinetics ye-plasma eqondile ngaphandle kokunqwabelana ngesikhathi somthamo omningi.