I-5-Fluoro-2-Oxindole CAS 56341-41-4 Ubumsulwa >99.0% (LCMS) I-Sunitinib Malate Intermediate Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-5-Fluoro-2-Oxindole (CAS: 56341-41-4) enekhwalithi ephezulu, ukukhiqizwa kwezentengiso.Wamukelekile eku-odeni.
Igama Lekhemikhali | 5-Fluoro-2-Oxindole |
Omqondofana | 5-Fluorooxindole;I-5-Fluoro-2-indolinone;I-5-Fluoroindolin-2-one;5-Fluoro-1,3-Dihydro-indol-2-one |
Inombolo ye-CAS | 56341-41-4 |
Inombolo yeCAT | I-RF-PI1543 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | C8H6FNO |
Isisindo samangqamuzana | 151.14 |
Ukuminyana | 1.311±0.06 g/cm3 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Ephuzi Ekhanyayo |
1 H NMR Spectrum | Ihambisana Nesakhiwo |
I-LCMS | Ihambisana Nesakhiwo |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (LCMS) |
I-Melting Point | 143.0~147.0℃ |
Ukulahlekelwa Ekumisweni | <0.50% |
Ukungcola Okuphelele | <1.00% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Abalamuli Bezemithi;I-Sunitinib Malate Intermediate |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-5-Fluoro-2-Oxindole (i-CAS: 56341-41-4) isetshenziswa kakhulu embonini yezemithi njengendawo emaphakathi yemithi.I-5-Fluoro-2-Oxindole iyindawo ephakathi ekuhlanganiseni kwe-Sunitinib Malate (CAS: 341031-54-7).I-Sunitinib Malate iwuhlobo lwemithi elwa nomdlavuza ehlosiwe kaningi futhi ingeye-tyrosine kinase inhibitor ehlosiwe eminingi enegama layo lokuhweba elithi “Suntent”.Yakhiwe ngempumelelo yiPfizer Company futhi inomphumela okabili wokulwa nesimila.Ngaphezu kwalokho, iwona kuphela umuthi wokwelapha ongadlula iminyaka emi-2 yokusinda komdlavuza wezinso othuthukile futhi udlala indima ebalulekile emkhakheni we-carcinoma kanye nezindawo zokwelapha ithumba le-stromal emathunjini.Yangena emakethe ngoFebhuwari 2006 e-United States.Lo muthi kwaba umuthi wokuqala wokulwa nomdlavuza owavunywa yi-US FDA futhi ungelapha izifo ezimbili ngasikhathi sinye.