5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid CAS 4242-18-6 Ubumsulwa >99.0% (HPLC) Palonosetron Hydrochloride Intermediate

Incazelo emfushane:

Igama: 5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid

Synonimes: 5,6,7,8-Tetrahydro-1-Naphthalenecarboxylic Acid

CAS: 4242-18-6

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: I-Crystalline Powder Emhlophe noma Cishe Emhlophe

Okumaphakathi kwePalonosetron Hydrochloride CAS 135729-62-3

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid (CAS: 4242-18-6) enekhwalithi ephezulu.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo kulo mkhiqizo, sicela uthumele imininingwane enemininingwane ehlanganisa inombolo ye-CAS, igama lomkhiqizo, nenani kithi.Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali 5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid
Omqondofana 5,6,7,8-Tetrahydro-1-Naphthalenecarboxylic Acid;5,6,7,8-Tetrahydro-Naphthalene-1-Carboxylic Acid;5,6,7,8-Tetrahydro-1-Naphthoic Acid
Isimo Sesitoko Esitokweni, Amandla Okukhiqiza Amathani
Inombolo ye-CAS 4242-18-6
I-Molecular Formula I-C11H12O2
Isisindo samangqamuzana 176.22
I-Melting Point 148.0~152.0℃
Iphuzu elibilayo 336.8±31.0℃
Ukuminyana 1.184±0.06 g/cm3
Isimo Sokuthumela Amazinga Okushisa e-Ambient
I-COA ne-MSDS Iyatholakala
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into

Izinga Lokuhlola

Imiphumela

Ukubukeka

I-Crystalline Powder Emhlophe noma Cishe Emhlophe

Kuthotshelwe

Ukulahlekelwa Ekumisweni

<1.00%

0.67%

Izinsalela ekushiseni

<0.20%

0.03%

I-Melting Point

148.0~152.0℃

149.9 ~ 150.9 ℃

Ubumsulwa (HPLC)

>99.0% (HPLC)

99.9%

Isivivinyo

98.0~101.0% (Neutralization Titration)

100.9%

1 H NMR Spectrum

Ihambisana Nesakhiwo

Isiphetho

Lo Mkhiqizo Ngokuhlola Uvumelana Nezinga Lebhizinisi

Ukusetshenziswa Okuyinhloko I-Intermediate ye-Palonosetron Hydrochloride (CAS: 135729-62-3)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile, eyomile futhi engenamoya kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

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Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

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I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

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Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

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Isicelo:

I-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid (CAS: 4242-18-6) iyindawo ephakathi esetshenziselwa ukulungiswa kwe-ejenti ye-antiemetic ewusizo yokwelapha i-Palonosetron Hydrochloride (CAS: 135729-62-3).I-Palonosetron Hydrochloride iyisidakamizwa sokuvimbela isicanucanu nokuhlanza, okuwuhlobo olusha olukhetha kakhulu, olusondelene kakhulu ne-5-HT3 receptor antagonist engavimba isikhungo sokuhlanza i-reflex peripheral neurons presynaptic 5-HT.Ukujabula kwesamukeli kuthinta ngokuqondile isimiso sezinzwa esimaphakathi ku-5-HT.Injabulo ye-impulse receptor ekhiqizwa indima ye-vagal afferent nerve ngemva kwendawo, ivimba iziphetho ze-vagus nerve emathunjini, ivimbela amasignali ku-5-HT.I-receptor trigger zone inganciphisa izehlakalo zokucanuzela kwenhliziyo nokuhlanza.Central Clinically yokwelashwa kwe-acute emetogenic chemotherapy ebangela ukubambezeleka kwesicanucanu nokuhlanza.Ngenxa yomphumela wayo ophezulu wokwelapha, umphumela omncane ongathandeki, impilo ende yesigamu (cishe 40 h), umthamo omncane, nokunye, kuye kwakhanga ukunaka okukhulu.

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