I-6-Aminohexanoic Acid CAS 60-32-2 (ε-Aminocaproic Acid) Assay 98.5~100.5% Factory

I-6-Aminohexanoic Acid (ε-Aminocaproic Acid) (CAS: 60-32-2) AJI97 Indlela Yokuhlola
I-ε-Aminocaproic Acid, uma ibalwa ngesisekelo se-anhydrous, iqukethe amaphesenti angekho ngaphansi kuka-98.5 futhi angabi ngaphezu kwamaphesenti angu-100.5 we-ε-Aminocaproic Acid (C6H13NO2).
Incazelo: Amakristalu amhlophe noma i-crystalline powder, ukunambitheka okubabayo kancane.
Incibilika ngokukhululeka emanzini naku-glacial acetic acid, inyibilika kancane ku-methanol, ayincibiliki ku-ethanol.
Ukunyibilika (H2O, g/100g): Incibilika ngokukhululeka emanzini
Ukuhlonza: Qhathanisa i-spectrum yokumuncwa kwe-infrared yesampula naleyo yezinga lendlela ye-potassium bromide disc.
Imininingwane:
Isimo Sesixazululo (Ukudluliswa): 0.5g ku-10ml ye-H2O, i-spectrophotometer, 430nm, 10mm ubukhulu beseli.
I-Chloride (Cl): 0.7g, A-1, ref: 0.40ml ka-0.01mol/L HCl
I-Ammonium (NH4): B-1
I-Sulfate (SO4): 1.2g, (1), ref: 0.50ml ka-0.005mol/L H2SO4
I-ayoni (Fe): 0.5g, ref: 1.5ml ye-Iron Std.(0.01mg/ml)
Izinsimbi Ezisindayo (Pb): 2.0g, (1), pH=7, ref: 2.0ml ye-Pb Std.(0.01mg/ml)
I-Arsenic (As2O3): 2.0g, (1), ref: 2.0ml ye-As2O3 Std.
Amanye ama-Amino Acids: Isampula yokuhlola: 100μg, B-1-a, ukulawula;ε-Acp 0.6μg
Amanzi: 500mg, i-methanol: i-ethyleneglycol (1:2) ye-Karl Fischer Method, A, imizuzu engu-15.
Izinsalela Ekushiseni (I-Sulfated): Ukuhlolwa kwe-AJI 13
I-Assay: Isampula ibalwe ngesisekelo se-anhydrous, 130mg, (1), 3ml ye-formic acid, 50ml ye-glacial acetic acid, 0.1mol/L HCLO4 1ml=13.117mg C6H13NO2
pH: 1.0g ku-10ml ye-H2O
Umkhawulo wokulondoloza onconyiwe nesimo: Iziqukathi ezigciniwe eziqinile ezingeni lokushisa elilawulwayo legumbi (iminyaka emi-2).

I-6-Aminohexanoic Acid (ε-Aminocaproic Acid) (CAS: 60-32-2) Indlela Yokuhlola ye-USP35
I-Aminocaproic Acid iqukethe okungengaphansi kwamaphesenti angu-98.5 futhi hhayi ngaphezu kwamaphesenti angu-101.5 we-C6H13NO2, abalwe ngesisekelo se-anhydrous.
Ukupakisha nokugcina-Londoloza ezitsheni eziqinile.Gcina ekamelweni lokushisa.
Amazinga ereferensi we-USP <11>-
USP Aminocaproic Acid RS
Ukuhlonza, Ukumuncwa kwe-Infrared <197K>.
Amanzi, Indlela I <921>: hhayi ngaphezu kuka-0.5%.
Izinsalela ekushiseni <281>: hhayi ngaphezu kuka-0.1%.
Izinsimbi ezinzima, Indlela II <231>: 0.002%.
Isivivinyo-
Isixazululo A-Dlulisa u-0.55 g we-sodium 1-heptanesulfonate ku-1000-mL ye-volumetric flask, hlakazeka bese uhlanza ngamanzi ngevolumu, bese uxuba.
Isigaba seselula-Dlulisa u-10 g we-monobasic potassium phosphate ku-beaker engu-1000-mL, ncibilika ku-300 mL Wesixazululo A, engeza u-250 mL we-methanol, ulandelwe omunye u-300 mL Wesixazululo A, bese uxuba.Lungisa ingxube nge-phosphoric acid ibe i-pH engu-2.2.Dlulisela yonke ingxube ku-1000-mL ye-volumetric flask, hlambulula nge-Solution A ibe yivolumu, bese uxuba.Isihlungi kanye ne-degas.Yenza izinguquko uma kudingeka (bona Ukufaneleka Kwesistimu ngaphansi kwe-Chromatography <621>).
Isixazululo sangaphakathi esijwayelekile-Lungisa isixazululo se-methionine emanzini ano-1.25 mg ngemL.
Ukulungiselela okujwayelekile-Chaza isamba esikalwe ngokunembile se-USP Aminocaproic Acid RS emanzini ukuze uthole isixazululo sesitoko esinengxube eyaziwayo engu-12.5 mg ngemL ngayinye.Dlulisa u-5.0 mL wesisombululo sesitoko ku-100-mL ye-volumetric flask, engeza u-2.0 mL wesixazululo esijwayelekile sangaphakathi, hlambulula ngamanzi ukuya kuvolumu, bese uxuba.
Ukulungiselela i-assay-Dlulisa inani elinesisindo esinembile lika-1.25 g we-Aminocaproic Acid ku-100-mL ye-volumetric flask, ncibilikisa futhi uhlambulule ngamanzi uye kuvolumu, bese uxuba.Dlulisa u-5.0 mL walesi sixazululo ku-100-mL ye-volumetric flask, engeza u-2.0mL wesixazululo esijwayelekile sangaphakathi, hlambulula ngamanzi ukuya kuvolumu, bese uxuba.
Isistimu ye-Chromatographic (bona i-Chromatography <621>)-I-chromatograph ewuketshezi ifakwe umtshina ongu-210-nm kanye nekholomu engu-4.6-mm × 15-cm equkethe ukupakisha i-L1 futhi igcinwa ku-30°.Izinga lokugeleza licishe libe ngu-0.7 ml ngomzuzu.I-Chromatograph Ukulungiselelwa Okujwayelekile, futhi urekhode izimpendulo eziphezulu njengoba kuqondiswe kuNqubo: izikhathi zokugcinwa okuhlobene zicishe zibe ngu-0.76 ku-aminocaproic acid kanye no-1.0 kwe-methionine;isinqumo, R, phakathi kwe-aminocaproic acid ne-methionine ayikho ngaphansi kuka-2.0;futhi ukuchezuka okujwayelekile okuhlobene kwemijovo eyimpinda akukho ngaphezu kuka-2.0%.
Inqubo-Ngokuhlukile jova amavolumu alinganayo (cishe u-20 µL) wokulungiswa Okujwayelekile kanye nokulungiswa kwe-Assay ku-chromatograph, futhi uvumele ukulungiswa kwe-Assay ukuthi kuphume isikhathi esingaphansi kwezikhathi ezimbili zokugcinwa kwe-aminocaproic acid.Rekhoda ama-chromatogram, futhi ulinganise zonke izimpendulo eziphezulu.Bala inani, ngo-g, le-C6H13NO2 engxenyeni ye-Aminocaproic Acid ethathwe ifomula:
2C(RU / RS)
lapho u-C ewukugxila, ngo-mg ngemL ngayinye, ye-USP Aminocaproic Acid RS ekulungiseleleni Okujwayelekile;kanye ne-RU kanye ne-RS izilinganiso zokuphendula okuphezulu kwe-aminocaproic acid kumpendulo ephakeme evamile yangaphakathi etholwe ekulungiselelweni kwe-Assay nasekulungiseleleni Okujwayelekile, ngokulandelanayo.