I-6-Mercaptopurine 6-MP CAS 50-44-2 Assay 97.0~102.0% Factory USP Standard
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali: 6-Mercaptopurine
CAS: 50-44-2
| Igama Lekhemikhali | 6-Mercaptopurine |
| Omqondofana | I-Mercaptopurine;6-MP;6-Mercaptopurine (monohydrate) |
| Inombolo ye-CAS | 50-44-2 |
| Inombolo yeCAT | I-RF-PI487 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C5H4N4S |
| Isisindo samangqamuzana | 152.18 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder Ephuzi |
| Isivivinyo | 97.0~102.0% |
| I-Melting Point | ≥300℃ |
| Ukungcola Okuguquguqukayo Kwezinto Eziphilayo | Hlangana Nemfuneko |
| Ukulahlekelwa Ekumisweni | ≤11.0% |
| Izinsalela ekushiseni | ≤0.20% |
| I-Hypoxanthine | ≤1.0% |
| Izinsimbi Ezisindayo | ≤10ppm |
| Izinga Lokuhlola | I-United States Pharmacopoeia (USP) |
| Ukusetshenziswa | I-API;Pharmaceutical Intermediates |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-6-Mercaptopurine (i-CAS: i-50-44-2) iyi-ejenti ye-antileukemic esetshenziswa kabanzi kanye nezidakamizwa ezivimbela i-novo purine synthesis ngokufaka i-thiopurine methyltransferase metabolites ku-DNA ne-RNA.I-6-Mercaptopurine iyi-analogue ye-purine esebenza njengomphikisi we-endogenous purines futhi isetshenziswe kabanzi njenge-antileukemic ejenti kanye nesidakamizwa sokuzivikela komzimba.I-Mercaptopurine ivimbela i-purine nucleotide synthesis kanye ne-metabolism ngokuvimbela i-enzyme ebizwa ngokuthi i-Phosphoribosyl pyrophosphate amidotransferase (PRPP Amidotransferase).I-Mercaptopurine iphazamisa ukuguqulwa kwe-nucleotide kanye nokuhlanganiswa kwe-glycoprotein.I-Mercaptopurine, ethengiswa ngaphansi kwegama lomkhiqizo i-Purinethol, ikakhulukazi isetshenziselwa ukwelapha i-acute lymphocytic leukemia (ALL), i-myeloid leukemia engapheli (CML), isifo sika-Crohn, kanye ne-ulcerative colitis.
