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I-6-O-Methylguanine CAS 20535-83-5 Isithombe Esifakiwe Sefektri Ephakathi Nelzarabine
  • I-6-O-Methylguanine CAS 20535-83-5 I-Nelzarabine Intermediate Factory

I-6-O-Methylguanine CAS 20535-83-5 I-Nelzarabine Intermediate Factory

Incazelo emfushane:

Igama Lekhemikhali: 6-O-Methylguanine

Synonyms: 2-Amino-6-Methoxypurine

I-CAS: 20535-83-5

I-Assay: ≥98.5% (HPLC)

Ukubukeka: I-Off-White Crystalline Powder

Okuphakathi kwe-Nelzarabine (CAS: 121032-29-9) ekwelapheni i-T-ALL & T-LBL

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Nikeza Ngokuhlanzeka Okuphezulu, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali: 6-O-Methylguanine
I-CAS: 20535-83-5

Chemical Properties:

Igama Lekhemikhali 6-O-Methylguanine
Omqondofana I-2-Amino-6-Methoxypurine
Inombolo ye-CAS 20535-83-5
Inombolo yeCAT I-RF-PI509
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C6H7N5O
Isisindo samangqamuzana 165.16
I-Melting Point >300℃ (okhanyayo)
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka I-Off-White Crystalline Powder
Indlela Yokuhlola / Yokuhlaziya ≥98.5% (HPLC)
Ukulahlekelwa Ekumisweni ≤0.50%
Izinsalela ekushiseni ≤0.50%
Ukungcola Okuphelele ≤1.5%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Okumaphakathi kwe-Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

1

I-FAQ:

Isicelo:

I-6-O-Methylguanine (i-CAS: 20535-83-5) ingasetshenziswa njengendawo ephakathi ekuhlanganiseni kwe-Nelzarabine (CAS: 121032-29-9).I-Nelarabine iyi-prodrug ye-deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).I-Nelarabine demethylates endimeni ye-adenosine deaminase (ADA) futhi iphenduka i-ara-G.I-Nelarabine yasungulwa ngempumelelo i-GlaxoSmithKline.Ngomhla zingama-28 kuMfumfu wezi-2005 ngaphansi kwemvume ye-US Food and Drug Administration, yaba umuthi omusha wokwelapha i-T-cell acute lymphoblastic leukemia (T-ALL) kanye ne-T-Cells lymphoblasticlymphoma (T-LBL) engazweli okungenani. izinhlobo ezimbili zemithi yokwelapha ngamakhemikhali noma eziphinde zabuyela emuva ngemva kokwelashwa kokuqala.Lesi sidakamizwa esisha esohlwini ngokusemthethweni e-United States ngo-2006.

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