6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9 PF-07321332 Boceprevir Intermediate
I-Commercial Supply PF-07321332 I-Paxlovid Izixhumanisi Ezihlobene Nekhwalithi Ephezulu
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(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
I-Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9
Igama Lekhemikhali | 6,6-Dimethyl-3-azabicyclo[3.1.0]hexane |
Inombolo ye-CAS | 943516-54-9 |
Inombolo yeCAT | I-RF-PI316 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C7H13N |
Isisindo samangqamuzana | 111.18 |
Iphuzu elibilayo | 135℃ |
Ukuminyana | 0.911 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Uketshezi Olungenambala Okungenambala |
Ubumsulwa | ≥98.0% |
Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤2.0% |
Izinsimbi Ezisindayo | ≤20ppm |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kanye ne-Boceprevir (CAS 394730-60-0) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane (CAS 943516-54-9) iphakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kanye ne-Boceprevir (CAS 394730-60-0).I-Pfizer's Paxlovid PF-07321332 iwukwelapha okwenziwa ngomlomo oqondiswe ku-SARS-CoV-2 betacoronavirus ukuvimbela i-COVID-19.I-Paxlovid iyi-protease inhibitor ebonise umsebenzi onamandla we-vitro antiviral ngokumelene ne-SARS-CoV-2 namanye ama-coronavirus, iphakamisa ukuthi kungenzeka isetshenziswe ekwelapheni i-COVID-19, kanye nokusetshenziswa okungaba khona ngokumelene nezinsongo zegciwane zesikhathi esizayo, kusho uPfizer.I-Boceprevir (EBP 520) iyi-inhibitor enamandla, ekhetha kakhulu, etholakala ngomlomo nge-bioavailable HCV NS3 ene-Ki ye-14 nM kukho kokubili ukuhlolwa kwe-enzyme kanye ne-EC90 ye-350 nM ekuhlolweni kwe-replicon okusekelwe kuseli.I-Boceprevir ivimbela umsebenzi we-SARS-CoV-2 3CLpro.