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I-7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Isithombe Esifakiwe Esimaphakathi se-Tolvaptan
  • 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate

7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate

Incazelo emfushane:

Igama: 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one

I-CAS: 160129-45-3

Ubumsulwa: ≥99.0% (HPLC)

Ukubukeka: Okuluhlaza Okukhanyayo kuya Kumpushana Ophuzi Okhanyayo

I-Intermediate of Tolvaptan (CAS 150683-30-0) yokwelashwa kwe-Hyponatremia

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com

 


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Ukunikezwa Komkhiqizi, Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo
I-Tolvaptan kanye Nezixhumanisi Ezihlobene:
I-Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
I-4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
I-2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5

Chemical Properties:

Igama Lekhemikhali 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
Omqondofana 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
Inombolo ye-CAS 160129-45-3
Inombolo yeCAT I-RF-PI395
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C10H10ClNO
Isisindo samangqamuzana 195.65
I-Melting Point 103.0 ukuze 107.0 ℃
Ukuncibilika I-Soluble ku-Methanol
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Okuluhlaza Okukhanyayo kuya Kumpushana Ophuzi Okhanyayo
Izindlela Zokuhlonza I-NMR, HPLC
Ukuhlanzeka / Indlela Yokuhlaziya ≥99.0% (HPLC)
Ukulahlekelwa Ekumisweni ≤1.0%
Izinsalela ekushiseni ≤0.50%
Noma Ikuphi Ukungcola Okukodwa ≤0.50%
Ukungcola Okuphelele ≤1.0%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate of Tolvaptan (CAS 150683-30-0), ukwelashwa kwe-Hyponatremia

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

1

I-FAQ:

Isicelo:

I-7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one (CAS 160129-45-3) iphakathi ekuhlanganiseni kwe-Tolvaptan (CAS 150683-30-0).I-Tolvaptan iyisithathisi esikhethiwe, esiqhudelanayo ngomlomo esingasebenzi i-arginine vasopressin V2 receptor antagonist ene-IC50 ye-1.28µM yokuvimbela ukuhlangana kweplatelet eyenziwe yi-AVP.I-Tolvaptan isetshenziselwa ukwelapha i-hyponatremia ehambisana nokuhluleka kwenhliziyo, i-cirrhosis, kanye ne-syndrome ye-antidiuretic hormone engafaneleki.U-Tolvaptan usezivivinyweni zomtholampilo ezisheshayo zesifo sezinso se-polycystic.Ukwelashwa nge-Tolvaptan kubangela ukuncipha kwesisindo somzimba ngokushesha nangokuqhubekayo okuhambisana nokwanda kokuphuma komchamo, kuthuthukisa kanye/noma kwenza kujwayelekile i-serum sodium ezigulini ezine-hyponatremic, kunciphisa izimpawu nezimpawu zokuminyana futhi kwandise ukoma.

Bhala umyalezo wakho lapha futhi usithumelele wona