7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity
Umkhiqizi Uhlinzeka Nge-Irinotecan kanye Nezixhumanisi Ezihlobene:
I-Irinotecan Hydrochloride CAS: 100286-90-6
I-Irinotecan Free Base CAS: 97682-44-5
I-Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
I-7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Igama Lekhemikhali | I-7-Ethyl-10-Hydroxycamptothecin |
Omqondofana | I-SN-38 |
Inombolo ye-CAS | 86639-52-3 |
Inombolo yeCAT | I-RF-PI242 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C22H20N2O5 |
Isisindo samangqamuzana | 392.41 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Yamakristalu Amhlophe Ngokukhanyayo |
Ukuhlonza (IR, UV) | (1) I-Ultraviolet ray ukumunca spectrum ngokuvumelana nezimfuno (2) I-infrared ray absorption spectrum concordant ne-reference standard spectrum kufanele ihambisane nokuhlolwa okugunyaziwe. |
I-Melting Point | 228.0~235.0℃ |
Izinto Ezihlobene | ≤1.5% |
I-10-Hydroxycamptothecin | ≤0.30% |
7-Cthylcamptothecin | ≤0.70% |
Ukungcola Okungaziwa Okuphezulu | ≤0.50% |
Ukulahlekelwa Ekumisweni | ≤1.0% |
Izinsimbi Ezisindayo | ≤10ppm |
Izinsalela ekushiseni | ≤0.10% |
Ukucaca Kwesixazululo | Kucace |
Isivivinyo | ≥98.0% (HPLC) |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Pharmaceutical Intermediate ye-Irinotecan |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
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I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) enekhwalithi ephezulu.I-7-Ethyl-10-Hydroxycamptothecin (i-CAS: 86639-52-3) iyi-metabolite esebenzayo ye-Topoisomerase I inhibitor Irinotecan.I-SN-38 (NK012) ivimbela ukuhlanganiswa kwe-DNA ne-RNA nge-IC50s ka-0.077 kanye no-1.3 μM, ngokulandelanayo.I-7-Ethyl-10-Hydroxycamptothecin (SN-38), iyi-metabolite esebenzayo ye-Irinotecan, okuphuma ku-semisynthetic ye-camptothecin, i-alkaloid esekelwe ku-quinoline etholakala emagxolweni esihlahla sase-Chinese camptotheca kanye nesihlahla sase-Asian nothapodytes.Nakuba i-7-Ethyl-10-Hydroxycamptothecin inamandla afika kwangu-1,000 kune-Irinotecan, ayikaguqulwa ibe ikhandidethi elisebenzayo lesidakamizwa ngenxa yokuthi ayincibiliki.Njengamanje ingaphansi kokuhlolwa komtholampilo ngokuhlanganiswe nezinye izingxenye ezingase ekugcineni ivumele ukuthi isebenze kahle njengomuthi we-antineoplastic.