7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity
Umkhiqizi Uhlinzeka Nge-Irinotecan kanye Nezixhumanisi Ezihlobene:
I-Irinotecan Hydrochloride CAS: 100286-90-6
I-Irinotecan Free Base CAS: 97682-44-5
I-Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
I-7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Igama Lekhemikhali | I-7-Ethyl-10-Hydroxycamptothecin |
| Omqondofana | I-SN-38 |
| Inombolo ye-CAS | 86639-52-3 |
| Inombolo yeCAT | I-RF-PI242 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C22H20N2O5 |
| Isisindo samangqamuzana | 392.41 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Yamakristalu Amhlophe Ngokukhanyayo |
| Ukuhlonza (IR, UV) | (1) I-Ultraviolet ray ukumunca spectrum ngokuvumelana nezimfuno (2) I-infrared ray absorption spectrum concordant ne-reference standard spectrum kufanele ihambisane nokuhlolwa okugunyaziwe. |
| I-Melting Point | 228.0~235.0℃ |
| Izinto Ezihlobene | ≤1.5% |
| I-10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| Ukungcola Okungaziwa Okuphezulu | ≤0.50% |
| Ukulahlekelwa Ekumisweni | ≤1.0% |
| Izinsimbi Ezisindayo | ≤10ppm |
| Izinsalela ekushiseni | ≤0.10% |
| Ukucaca Kwesixazululo | Kucace |
| Isivivinyo | ≥98.0% (HPLC) |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Pharmaceutical Intermediate ye-Irinotecan |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) enekhwalithi ephezulu.I-7-Ethyl-10-Hydroxycamptothecin (i-CAS: 86639-52-3) iyi-metabolite esebenzayo ye-Topoisomerase I inhibitor Irinotecan.I-SN-38 (NK012) ivimbela ukuhlanganiswa kwe-DNA ne-RNA nge-IC50s ka-0.077 kanye no-1.3 μM, ngokulandelanayo.I-7-Ethyl-10-Hydroxycamptothecin (SN-38), iyi-metabolite esebenzayo ye-Irinotecan, okuphuma ku-semisynthetic ye-camptothecin, i-alkaloid esekelwe ku-quinoline etholakala emagxolweni esihlahla sase-Chinese camptotheca kanye nesihlahla sase-Asian nothapodytes.Nakuba i-7-Ethyl-10-Hydroxycamptothecin inamandla afika kwangu-1,000 kune-Irinotecan, ayikaguqulwa ibe ikhandidethi elisebenzayo lesidakamizwa ngenxa yokuthi ayincibiliki.Njengamanje ingaphansi kokuhlolwa komtholampilo ngokuhlanganiswe nezinye izingxenye ezingase ekugcineni ivumele ukuthi isebenze kahle njengomuthi we-antineoplastic.
