I-7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2 Purity >99.5% (HPLC) I-Agomelatine Intermediate Factory

Incazelo emfushane:

Igama: 7-Methoxy-1-Naphthaleneacetic Acid

Synonyms: (7-Methoxy-1-Naphthyl)i-acetic Acid

I-CAS: 6836-22-2

Ubumsulwa: >99.5% (HPLC)

Ukubukeka: Impushana Eqinile Ephuzi Ekhanyayo

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

I-Intermediate ye-Agomelatine (CAS: 138112-76-2)

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E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi Oholayo Nomhlinzeki Wezinto Ezimaphakathi ze-Agomelatine
I-Agomelatine CAS 138112-76-2
I-7-Methoxy-1-Tetralone CAS 6836-19-7
I-7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
I-7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali I-7-Methoxy-1-Naphthaleneacetic Acid
Omqondofana (7-Methoxy-1-Naphthyl)i-acetic Acid;I-2-(7-Methoxynaphthalen-1-yl)i-acetic Acid;2-(7-Methoxy-1-Naphthyl)i-acetic Acid
Inombolo ye-CAS 6836-22-2
Inombolo yeCAT I-RF2688
Isimo Sesitoko Esitokweni, Amandla Okukhiqiza Amathani angama-20 ngenyanga
I-Molecular Formula I-C13H12O3
Isisindo samangqamuzana 216.24
I-Melting Point 153.0 ukuze 158.0 ℃
Iphuzu elibilayo 408.8±20.0℃
Ukuminyana 1.235
Ukuncibilika I-Soluble ku-Methanol
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Eqinile Ephuzi Ekhanyayo
Ukuhlanzeka / Indlela Yokuhlaziya >99.5% (HPLC)
I-Melting Point 153.0 ~ 158.0℃
Ukulahlekelwa Ekumisweni <0.50%
Izinsalela ekushiseni <0.20%
Ukungcola Okukodwa <0.50%
Ukungcola Okuphelele <0.50%
1 H NMR Spectrum Ihambisana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Pharmaceutical Intermediate ye-Agomelatine (CAS: 138112-76-2)

Iphakheji nesitoreji:

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Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

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Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

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Isicelo:

I-7-Methoxy-1-Naphthaleneacetic Acid (CAS: 6836-22-2) iyi-intermediate ye-Agomelatine (CAS: 138112-76-2).I-Agomelatine iyi-antidepressant esetshenziselwa ukwelapha ukudangala.Ubuchopho buvame ukwenza isiqiniseko sokuthi sinamakhemikhali anele esiwadingayo ukuze sisebenze kahle.Kodwa ukucindezeleka kungathinta inqwaba yamakhemikhali obuchopho.Lawa makhemikhali ahlanganisa i-noradrenaline, i-dopamine ne-serotonin;ukucindezeleka kunciphisa amazinga alaba bathumeli bobuchopho.Ukucindezeleka kuphinde kuthinte ikhemikhali ebizwa ngokuthi i-melatonin.I-melatonin encishisiwe ihlotshaniswa nokuphazamiseka kwendlela yethu yokulala.I-Agomelatine iyi-antidepressant yokuqala yokwandisa umsebenzi we-melatonin ngokuqondile.Lokhu ikwenza ngokwenza njenge-melatonin ezindaweni eziqondiwe lapho i-melatonin isebenza khona.(Lezi zaziwa ngokuthi ama-melatonin receptors).Ngokwandisa umsebenzi we-melatonin, i-agomelatine iphinde ikhulise ngokuqondile umsebenzi we-noradrenaline ne-dopamine.I-Agomelatine inemiphumela ethile yokulwa nokukhathazeka, ikhulula ukuqwasha kubantu abanokucindezeleka.I-Agomelatine ilawula umjikelezo wokulala nokuvuka komzimba.I-Agomelatine iyimpumelelo ekwelapheni ukudangala.I-Agomelatine ithuthukiswe yinkampani eyenza imithi iServier.Imakethwa ukuze zelashwe ukuphazamiseka okukhulu kokucindezeleka futhi kubikwe ukuthi ayikhiqizi i-discontinuation syndrome futhi ayinayo imiphumela emibi yocansi uma iqhathaniswa nama-SSRIs, ama-SNRI kanye nama-antidepressants amadala e-tricyclic.I-Agomelatine ingase futhi ibe nemiphumela emihle ekulaleni.

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