7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Purity >99.0% (GC) Agomelatine Intermediate
Umkhiqizi Oholayo Nomhlinzeki Wezinto Ezimaphakathi ze-Agomelatine
I-Agomelatine CAS 138112-76-2
I-7-Methoxy-1-Tetralone CAS 6836-19-7
I-7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
I-7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester |
| Omqondofana | I-Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate |
| Inombolo ye-CAS | 6836-21-1 |
| Inombolo yeCAT | RF2687 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C15H16O3 |
| Isisindo samangqamuzana | 244.29 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Uketshezi Olukhanyayo Oluphuzi Olukhanyayo |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (GC) |
| Amanzi (nguKarl Fischer) | <0.50% |
| Izinto Ezihlobene | <1.00% |
| I-Infrared Spectrum | Ivumelana Nesakhiwo |
| I-NMR Spectrum | Ivumelana Nesakhiwo |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Pharmaceutical Intermediate ye-Agomelatine (CAS: 138112-76-2) |
Iphakheji: I-Fluorinated Ibhodlela, 25kg/Umgqomo, noma ngokwezidingo zekhasimende
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Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eRussia, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) iyinhlangano ewusizo ye-organic synthetic intermediate, ingasetshenziswa njengendawo emaphakathi yemithi ye-Agomelatine (CAS: 138112-76-2).I-Agomelatine, ethuthukiswe inkampani yase-French Servier, iyi-melatonin receptors yokuqala emhlabeni i-MT1 kanye nekilasi le-agonist le-MT2 lama-antidepressants.Kusebenza ekwelapheni iziguli ezindala ezinokucindezeleka okukhulu.I-Agomelatine iyisidakamizwa esidambisa ukucindezeleka.I-Agomelatine i-agonist ye-melatonin (MT) receptors kanye nokuphuma kokunye kwe-melatonin.Ibophezela kuma-receptors e-MT1 kanye ne-MT2 (Kis = 0.14 kanye no-0.41 nM, ngokulandelanayo) futhi inevelu ye-EC50 engu-0.1 nM [35S]GTPγS ekuhlolweni okubophezelayo kusetshenziswa amaseli e-CHO aveza ama-receptors e-MT2.Ihlukaniswa njenge-norepinephrine-dopamine disinhibitor (NDDI) ngenxa yokuphikiswa kwayo kwesamukeli se-5-HT2C.Ukusebenza kwe-5-HT2C receptors nge-serotonin kuvimbela i-dopamine nokukhululwa kwe-norepinephrine.
