7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3 Purity >99.0% (HPLC) Agomelatine Intermediate

Incazelo emfushane:

Igama Lekhemikhali: 7-Methoxy-1-Naphthylacetonitrile

Amazwi afanayo: 7-Methoxy-1-Naphthylmethylcyanide

I-CAS: 138113-08-3

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: Impushana Ephuzi Ekhanyayo

I-Intermediate ye-Agomelatine (CAS: 138112-76-2)

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E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi Oholayo Nomhlinzeki Wezinto Ezimaphakathi ze-Agomelatine
I-Agomelatine CAS 138112-76-2
I-7-Methoxy-1-Tetralone CAS 6836-19-7
I-7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
I-7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali 7-Methoxy-1-Naphthylacetonitrile
Omqondofana I-7-Methoxy-1-Naphthylmethylcyanide;7-Methoxy-1-Naphthaleneacetinitrile;1-Cyanomethyl-7-Methoxynaphthalene;2-(7-Methoxy-1-Naphthyl)i-acetonitrile;2-(7-Methoxynaphthalen-1-yl)acetonitrile;Ukungcola kwe-Agomelatine 12;I-Agomelatine Intermediate 1
Inombolo ye-CAS 138113-08-3
Inombolo yeCAT I-RF2504
Isimo Sesitoko Esitokweni, Amandla Okukhiqiza Amathani angama-30 ngenyanga
I-Molecular Formula I-C13H11NO
Isisindo samangqamuzana 197.24
I-Melting Point 83.0 ukuze 86.0℃
Ukuminyana 1.135±0.06 g/cm3
I-Refractive Index n20/D 1.44
Ukuncibilika I-Soluble ku-Methanol
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Ephuzi Ekhanyayo
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (HPLC)
I-Melting Point 83.0~86.0℃
Ukulahlekelwa Ekumisweni <0.50%
Izinsalela ekushiseni <0.20%
Ukungcola Okukodwa <0.50%
Ukungcola Okuphelele <1.00%
Izinsimbi Ezisindayo <20ppm
I-Proton NMR Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Abalamuli Bezemithi;I-Agomelatine Intermediate

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

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Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

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Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

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Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.

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Isicelo:

I-7-Methoxy-1-Naphthylacetonitrile (CAS: 138113-08-3) iyi-intermediate ye-Agomelatine (CAS: 138112-76-2).I-Agomelatine, ethuthukiswe inkampani yase-French Servier, iyi-melatonin receptors yokuqala emhlabeni i-MT1 kanye nekilasi le-agonist le-MT2 lama-antidepressants.I-Agomelatine isebenza ekwelapheni iziguli ezikhulile ezinokucindezeleka okukhulu.I-Agomelatine iyi-antidepressant entsha enezenzo ezikhethiwe ze-agonist kuma-melatonin receptors kanye nesenzo esikhethiwe somphikisi kuma-serotonin 5HT-2C receptors.Akuthinti ukutholwa kwe-serotonin, i-noradrenaline noma i-dopamine.I-Agomelatine ingasiza ekulawuleni 'iwashi lakho lomzimba' (isigqi se-circadian) ngezinzuzo ezinhle ekucindezelekeni kwemizwa kanye ne-sleein I-Agomelatine isetshenziswa ekwelapheni ukudangala noma ukusiza ukuvimbela ukubuya kokudangala, futhi itholakala yodwa kanye nencwadi kadokotela.I-Agomelatine - Ukugula Ngengqondo Esinye isigaba sezidakamizwa "se-blockbuster".I-Agomelatine ine-antidepressant, anti-anxiety, elungisa isigqi sokulala futhi ilawula indima yewashi lebhayoloji, kanye nokusabela kwayo okubi, ukusebenza kocansi ngaphandle kwemiphumela emibi, futhi akukho mpendulo yokuhoxa.I-Agomelatine inomphumela omuhle ezigulini ezinokucindezeleka, futhi ukusabela okubi kuncane kakhulu.Umthamo onconyiwe we-Agomelatine ngokuvamile ungu-25mg nsuku zonke phakathi nesigamu sehora ngaphambi kokulala.

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