7-Methoxy-1-Tetralone CAS 6836-19-7 Purity >99.0% (GC) I-Agomelatine Intermediate Factory

Incazelo emfushane:

Igama Lekhemikhali: 7-Methoxy-1-Tetralone

CAS: 6836-19-7

Ubumsulwa: >99.0% (GC)

Ukubukeka: Amakristalu Amhlophe kuya Kunsundu noma Impushana

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

I-Intermediate ye-Agomelatine (CAS: 138112-76-2)

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E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi Oholayo Nomhlinzeki Wezinto Ezimaphakathi ze-Agomelatine
I-Agomelatine CAS 138112-76-2
I-7-Methoxy-1-Tetralone CAS 6836-19-7
I-7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
I-7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali I-7-Methoxy-1-Tetralone
Omqondofana 3,4-Dihydro-7-Methoxy-1(2H)-Naphthalenone;7-Methoxy-3,4-Dihydro-2H-Naphthalen-1-one;I-7-Methoxy-1-oxo-Tetralin;7-Methoxy-1,2,3,4-Tetrahydronaphthalene-1-one;7-Methoxy-1-Oxotetraline;7-Methoxy-1-Tetralinone;I-7-Methoxytetralin-1-one;I-Agomelatine Intermediate B
Inombolo ye-CAS 6836-19-7
Inombolo yeCAT RF2689
Isimo Sesitoko Esitokweni, Amandla Okukhiqiza Amathani angama-30 ngenyanga
I-Molecular Formula I-C11H12O2
Isisindo samangqamuzana 176.22
I-Melting Point 60.0 ukuze 64.0℃
Ukuminyana 1.124±0.06 g/cm3
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Amakristalu Amhlophe kuya Kunsundu noma Impushana
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (GC)
I-Melting Point 60.0 ukuze 64.0℃
Amanzi (nguKarl Fischer) <0.50%
Izinsalela ekushiseni <0.10%
Ukungcola Okukodwa <0.50%
Ukungcola Okuphelele <1.00%
I-Infrared Spectrum Ivumelana Nesakhiwo
I-Proton NMR Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Pharmaceutical Intermediate;I-Agomelatine (CAS 138112-76-2) Emaphakathi

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Izinzuzo:

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Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

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Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

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Isicelo:

I-7-Methoxy-1-Tetralone (CAS: 6836-19-7) iyi-intermediate ye-Agomelatine (CAS: 138112-76-2).I-Agomelatine iyi-antidepressant ye-melatonergic eyakhiwe inkampani eyenza imithi i-Servier.Imakethwa ukuze zelashwe ukuphazamiseka okukhulu kokucindezeleka futhi kubikwe ukuthi ayikhiqizi i-discontinuation syndrome futhi ayinayo imiphumela emibi yocansi uma iqhathaniswa nama-SSRIs, ama-SNRI kanye nama-antidepressants amadala e-tricyclic.I-Agomelatine ingase futhi ibe nemiphumela emihle ekulaleni.1. Njenge-Pharmaceutical, i-Agomelatine isetshenziswa ekwelapheni ukuphazamiseka okukhulu kokucindezeleka, ukuphazamiseka kwemizwelo.2. I-Agomelatine isetshenziselwa ukwelapha ukuphazamiseka okukhulu kokucindezeleka, ukuphazamiseka kwemizwelo.Isithako somuthi sohlelo lwezinzwa.I-antidepressant, i-anxiolytic, ilungisa isigqi sokulala kanye nokulawula iwashi lebhayoloji.3. I-Agomelatine iyi-agonist ye-melatoninergic kanye nomphikisi okhethiwe we-5-ht2c receptors.4. I-Agomelatine iyisidakamizwa esidambisa ukucindezeleka.Ihlukaniswa njenge-norepinephrine-dopamine disinhibitor (NDDI) ngenxa yokuphikiswa kwayo kwesamukeli se-5-HT2C.5. I-Agomelatine futhi iyi-agonist enamandla kuma-melatonin receptors okwenza kube isinqamuli sokucindezeleka sokuqala se-melatonergic.

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