Abacavir CAS 136470-78-5 Assay 99.0%~101.0% API Factory anti-HIV
Ukunikezela Komkhiqizi Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Abacavir
I-CAS: 136470-78-5
I-nucleoside analog reverse transcriptase inhibitor (NRTI) enamandla esetshenziselwa ukwelapha i-HIV ne-AIDS.
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali | Abacavir |
Inombolo ye-CAS | 136470-78-5 |
Inombolo yeCAT | I-RF-API62 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
I-Molecular Formula | I-C14H18N6O |
Isisindo samangqamuzana | 286.33 |
I-Melting Point | 165℃ |
Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
Ukuhlonza | (1) IR (2) HPLC (3) Sulfate |
Amanzi | ≤0.50% |
Izinsalela ku-Ingnition | ≤0.20% |
Umkhawulo we-Abacavir Enantiomer | ≤0.20% |
1) Izinto Ezihlobene | |
I-Descyclopropyl Abacavir | ≤0.20% |
I-Trans-Abacavir | ≤0.20% |
O-Pyrimidinyl Abacavir | ≤0.20% |
t-Butyl Derivate Abacavir | ≤0.20% |
Noma yikuphi Ukungcola Okungacacisiwe | ≤0.10% |
Ukungcola Okuphelele | ≤0.80% |
2) Ukuhlanzeka kwe-Enantiomeric | I-Abacavir Enantiomer ≤0.20% |
3) Izincibilikisi Ezisele | |
I-Methanol | ≤0.30% |
I-acetone | ≤0.50% |
I-Ethanol | ≤0.50% |
Izinsimbi Ezisindayo | ≤20ppm |
Isivivinyo | 99.0%~101.0% (kubalwe ngesisekelo se-anhydrous ne-solvent free) |
Izinga Lokuhlola | I-United States Pharmacopeia (USP) Standard |
Ukusetshenziswa | I-API;anti-HIV |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
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I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-Abacavir (CAS: 136470-78-5) enekhwalithi ephezulu.I-Abacavir API iyi-carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor (NRTI) kanye nomuthi olwa ne-HIV osetshenziselwa ukwelapha ukutheleleka nge-HIV.Ama-NRTI asebenza ngokuvimba i-HIV reverse transcriptase, i-enzyme ye-HIV.Lo mkhiqizo uhloselwe ukwelapha abantu abadala abangenwe i-human immunodeficiency virus (HIV).Izingxenye ezintathu ezingaguquki (i-Abacavir, i-Lamivudine, ne-Zidovudine) zisetshenziswa esikhundleni se-monotherapies emithathu ngemithamo efanayo.I-Abacavir, i-Lamivudine, ne-Zidovudine iyodwa inconywa amasonto angu-6-8 ekuqaleni kokwelashwa.
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