I-Anastrozole CAS 120511-73-1 API Factory High Quality

Incazelo emfushane:

Igama: Anastrozole

I-CAS: 120511-73-1

Ukubukeka: I-Crystalline Powder Emhlophe ukuya Kokumhlophe

Isilinganiso: 98.0%~102.0%

I-AnastrozoleUkwelapha Umdlavuza Webele

Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Inquiry: alvin@ruifuchem.com

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Incazelo:

Ukunikezela Komkhiqizi Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Anastrozole
I-CAS: 120511-73-1

Chemical Properties:

Igama	I-Anastrozole
Omqondofana	I-Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl) -1,3-benzenediacetonitrile
Inombolo ye-CAS	120511-73-1
Inombolo yeCAT	I-RF-API74
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu
I-Molecular Formula	I-C17H19N5
Isisindo samangqamuzana	293.37
Ukuncibilika	I-Soluble ku-DMSO ne-Ethanol
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder emhlophe ukuya kokumhlophe
Ukuhlonza A	I-IR/MS Ihambisana nezinga lokubhekisela
Ukuhlonza B	I-HPLC kanye nesimo esiphezulu: Ihambisana nereferensi
I-Melting Point	81.0 ~ 84.0℃
Okuqukethwe kwamanzi (nge-KF)	≤0.30%
Izinsalela ekushiseni	≤0.10%
Ukulahlekelwa Ekumisweni	≤0.50%
Izinsimbi Ezisindayo	≤10ppm
Izinto Ezihlobene
Ukungcola A	≤0.10%
Ukungcola B	≤0.20%
Ukungcola C	≤0.20%
Ukungcola D	≤0.10%
Ukungcola E	≤0.10%
Okunye Ukungcola Okukodwa	≤0.10%
Ukungcola Okuphelele	≤0.50%
Izincibilikisi Ezisele
I-Cyclohexane	≤0.30%
I-Ethyl Acetate	≤0.50%
Isivivinyo	98.0%~102.0% (komisiwe)
I-Shelf Life	Izinyanga ezingama-24
Izinga Lokuhlola	Izinga lebhizinisi;I-United States Pharmacopoeia (USP) Standard
Ukusetshenziswa	Ukwelapha Umdlavuza Webele

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-Anastrozole (CAS 120511-73-1), iyi-non-steroidal, yesizukulwane sesithathu sokuphuma kwe-achiral triazole emakethe njenge-ARIMIDEX® yi-AstraZeneca Pharmaceuticals LP1.Ingenye yesizukulwane sesithathu se-aromatase inhibitor okuyi-inhibitor yokuncintisana kakhulu futhi ekhethiwe ye-aromatase, ngaleyo ndlela ivimbela ukuguqulwa kwe-testosterone ku-estradiol ne-androstenedione ku-estrone.Ukuvinjelwa kwe-enzyme ye-aromatase kwenzeka ikakhulukazi ngokuncintisana okubophezeleka kwe-aromatase ku-hemegroup ye-cytochrome P450, ukuncipha kwe-estrogen biosynthesis ezicutshini ezijikelezayo zomzimba nasesifubeni.

I-Anastrozole iyindlela yokwelapha ebekezelelwa kahle yomdlavuza webele osesigabeni sokuqala.Njengamanye ama-aromatase inhibitors, umphumela wawo omubi obaluleke kakhulu kwaba ingozi eyengeziwe yokuphuka kwamathambo, okuthi i-anastrozole ivinjelwe esikhathini sokwelashwa.Inobuthi obuncane uma iqhathaniswa nokwelashwa ngamakhemikhali;kodwa-ke, kuye kwaphawulwa ukuthi iziguli eziningi ezilashwa nge-anastrozole zikhala ngezimpawu ezihlangene kunalokho obekulindelwe, ikakhulukazi ukuqina kwedijithali okufana ne-rheumatoid arthritis.Ezinye izivivinyo zomtholampilo ze-anastrozole kwabesifazane abangemva kokuya esikhathini abanomdlavuza webele eYurophu nase-United States babike ukuphazamiseka kwemisipha njengezehlakalo ezimbi.I-Anastrozole (i-Arimidex®) iyi-aromatase inhibitor evunyelwe e-EU, e-US nakwamanye amazwe emhlabeni jikelele ukuze isetshenziswe njengokwelashwa kwe-adjuvant kwabesifazane abangemva kokuya esikhathini abanomdlavuza webele we-hormone receptor-positive.Igunyazwe futhi e-EU nakwamanye amazwe emhlabeni jikelele ngokuqhubeka nokwelashwa kwe-adjuvant kwabesifazane asebevele beneminyaka engu-2-3 yokwelashwa kwe-adjuvant tamoxifen yomdlavuza webele.