I-Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant
Umkhiqizi Supply Argatroban Related Intermediate:
I-Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
I-3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
I-Argatroban Monohydrate CAS 141396-28-3
I-Argatroban Anhydrous CAS 74863-84-6
| Igama Lekhemikhali | I-Argatroban |
| Omqondofana | I-Argatroban Anhydrous |
| Inombolo ye-CAS | 74863-84-6 |
| Inombolo yeCAT | I-RF-API67 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
| I-Molecular Formula | I-C23H36N6O5S |
| Isisindo samangqamuzana | 508.63 |
| I-Melting Point | 188.0~189.0℃ |
| Iphuzu elibilayo | 801.3ºC ku-760 mmHg |
| Ukuminyana | 1.47 g/cm3 |
| Isimo Sokuthumela | Kuthunyelwe Ngaphansi Kwezinga Lokushisa Le-Ambient |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
| Ukuhlonza HPLC | Isikhathi sokugcinwa kwenani eliphakeme lomgomo elitholwe kusixazululo sokuhlola sihambisana nalelo elitholwe kusixazululo esijwayelekile, njengokuhlola ku-Assay |
| Ukuhlonza IR | Ihambisana ne-IR Spectrum ye-AG RS |
| Ukuhlonza UV | Endaweni engu-259nm kanye ne-332nm wavelength kufanele ibe nokumuncwa okuphezulu |
| Amanzi | 2.5-4.5% |
| Umbala Wesixazululo Nokucaca | Isixazululo Kufanele sibe Imibala Ecacile |
| Izinto Ezihlobene | |
| Ukungcola A + Ukungcola H | ≤0.10% |
| Ukungcola B | ≤0.10% |
| Ukungcola C + Ukungcola E | ≤0.10% |
| Ukungcola D | ≤0.10% |
| Ukungcola I | ≤0.10% |
| I-Bach Yokungcola Okungacacisiwe | ≤0.10% |
| Ukungcola Okuphelele | ≤0.30% |
| Izincibilikisi Ezisele | |
| I-Methanol | ≤3000ppm |
| I-Ethanol | ≤5000ppm |
| I-Dichloromethane | ≤600ppm |
| I-Ethyl Acetate | ≤5000ppm |
| I-Enantiomer (HPLC) | ≤0.10% |
| I-Isomer Ratio (HPLC) | 30.0%-40.0% |
| I-Chloride | ≤0.01% |
| Izinsalela ekushiseni | ≤0.10% |
| Izinsimbi Ezisindayo | ≤10ppm |
| Ama-bacterium Endotoxins | <5EU/mg |
| Umkhawulo weMicrobial | I-TAMC ≤1000 cfu/g |
| Isivivinyo | 98.0% -102.0% (kwisisekelo se-anhydrous) |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-API, i-Synthetic Antithrombotic Agent Anticoagulant |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nomphakeli we-Argatroban (CAS: 74863-84-6) enekhwalithi ephezulu, i-API.
I-Argatroban (CAS: 74863-84-6) iyi-ejenti entsha yokwenziwa ye-antithrombotic ewusizo ekunakekeleni i-anticoagulation kubo ischemic stroke kanye nokusabalalisa ukuhlangana kwe-intravascular coagulation.Kuyi-anticoagulant eyi-molecule encane eqondile ye-thrombin inhibitor.Ngo-2000, i-argatroban yanikezwa ilayisense yi-Food and Drug Administration (FDA) ye-prophylaxis noma ukwelashwa kwe-thrombosis ezigulini ezine-heparin-induced thrombocytopenia (HIT).Ngo-2002, yagunyazwa ukuthi isetshenziswe ngesikhathi sokungenelela kwe-coronary percutaneous ezigulini ezine-HIT noma ezisengozini yokuyithuthukisa.Ngo-2012, yagunyazwa yi-MHRA yase-UK ye-anticoagulation ezigulini ezine-heparin-induced thrombocytopenia Type II (HIT) ezidinga ukwelashwa kwe-parenteral antithrombotic.
