I-Aripiprazole Intermediate CAS 129722-34-5 Purity >98.0% (HPLC)
Abahlinzeki Bempahla Abaphakathi Be-Aripiprazole Ngokuhlanzeka Okuphezulu
I-Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2
I-7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Igama Lekhemikhali | 7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone |
| Omqondofana | 7-(4-Bromobutoxy) -3,4-Dihydroquinolin-2(1H) -enye;7-(4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7-(4-Bromobutoxy)-2(1H)-Quinolinone;I-Aripiprazole Ukungcola 3 |
| Inombolo ye-CAS | 129722-34-5 |
| Inombolo yeCAT | I-RF-PI2269 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C13H16BrNO2 |
| Isisindo samangqamuzana | 298.18 |
| Ukuminyana | 1.383 g/cm3 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystal Powder Emhlophe noma Ephuzi Ephuzi |
| Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) |
| I-Melting Point | 110.0~114.0℃ |
| Ukulahlekelwa Ekumisweni | <1.00% |
| Izinsalela ekushiseni | <0.50% |
| Izinsimbi Ezisindayo (njenge-Pb) | ≤20ppm |
| I-Proton NMR Spectrum | Ivumelana Nesakhiwo |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Intermediate ye-Aripiprazole (CAS: 129722-12-9) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-7-(4-Bromobutoxy)-3,4-Dihydro-2 (1H)-Quinolinone (CAS: 129722-34-5) iphakathi ekuhlanganiseni kwe-Aripiprazole (CAS: 129722-12-9).Umkhiqizo wokuwohloka kumathebulethi we-Aripiprazole.I-Aripiprazole (Abilify).Okusha kakhulu, i-longactingaripiprazole (okuphuma kuyo i-arylpiperazine quinolinone), kubonakala kuyi-agonist ingxenye yama-D2 receptors (okungukuthi, ivuselela ama-D2 receptors athile kuyilapho ivimba amanye kuye ngendawo yawo ebuchosheni kanye nokugcwala komuthi).I-Bioavailability ye-Aripiprazole icishe ibe ngu-87%, kanti ukugxila okuphezulu kwe-plasma kufinyelelwa emahoreni ama-3 kuye kwangama-5 ngemuva kokuphathwa.I-metabolized nge-dehydrogenation, i-oxidative hydroxylation, ne-N-dealkylation, ikakhulukazi exhunywe yi-CYPs ye-hepatic 3A4 ne-2D6.Ukwelashwa kwe-schizophrenia kanye nokuphazamiseka kwengqondo okuhlobene.I-dopamine D2-receptor antagonist ekhethiwe enomsebenzi we-agonist we-dopamine autoreceptor.I-Antipsychotic.
