I-Atazanavir Sulfate CAS 229975-97-7 Purity ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor

Incazelo emfushane:

Igama Lekhemikhali: Atazanavir Sulfate

I-CAS: 229975-97-7

Ukubukeka: Impushana Emhlophe noma Engamhlophe

Ubumsulwa: ≥99.0%

I-HIV-1 Protease Inhibitor

Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Inquiry: alvin@ruifuchem.com

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Imininingwane Yomkhiqizo

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Incazelo:

Nikeza Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Atazanavir Sulfate
I-CAS: 229975-97-7
I-HIV-1 Protease Inhibitor
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Chemical Properties:

Igama Lekhemikhali	I-Atazanavir sulfate
Omqondofana	I-BMS-232632 Sulfate
Inombolo ye-CAS	229975-97-7
Inombolo yeCAT	I-RF-API71
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu
I-Molecular Formula	I-C38H52N6O7.H2SO4
Isisindo samangqamuzana	802.93
I-Melting Point	195.0 ~ 198.0℃
Ukuncibilika	Ayincibiliki Emanzini, Ayincibiliki ku-DMSO
Isitoreji Sesikhathi Eside	Gcina Isikhathi Eside ku -20 ℃
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe noma Engamhlophe
I-sulfate	12.0~12.5%
Ukulahlekelwa Ekumisweni	≤0.50%
Izinsalela ekushiseni	≤0.10%
Izinsimbi Ezisindayo	≤20ppm
Ukungcola Okukodwa	≤0.30%
Ukungcola Okuphelele	≤1.0%
Ukuhlanzeka/Ukuhlaziya Indlela	≥99.0% (HPLC)
pH	5.0~8.0
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-HIV-1 Protease Inhibitor Anti-HIV

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) iwusawoti we-sulfate we-atazanavir ekhetha kakhulu i-HIV-1 protease inhibitor, iyi-protease inhibitor yokuqala egunyazwe ukusetshenziswa kanye ngosuku.I-Atazanavir Sulfate iyi-substrate kanye ne-inhibitor ye-CYP3A4, kanye ne-inhibitor kanye ne-inducer ye-P-glycoprotein (P-gp).I-Atazanavir Sulfate iphinde ibe yi-SARS-CoV 3CLpro inhibitor ene-IC50 ye-3.49 μM.I-Atazanavir Sulfate iyi-azapeptide kanye ne-HIV-protease inhibitor esetshenziswa ekwelapheni ukutheleleka nge-HIV kanye nengculazi ngokuhlangana namanye ama-Anti-HIV Agents, yakhiwe futhi yethulwa ngabakwaBristol-Myers Squibb (BMS), ngaphansi kwelayisensi yomhlaba wonke evela kwaNovartis, ekwelapheni ukutheleleka nge-HIV.I-Atazanavir yethulwa e-US njenge-Reyataz™ ngoJulayi 2003. I-Antiviral.I-Atazanavir ikhombise ukuthi inamandla kakhulu kunezinhlanu ezigunyazwe njengamanje i-HIV-1 protease inhibitors.I-Atazanavir ivimbela ngokukhethekile ukucutshungulwa kwegciwane okuqondene ngqo negciwane le-Gag ne-Gag-Pol polyprotein kumaseli ane-HIV-1 ngokubophezela endaweni esebenzayo ye-HIV-1 protease, ngaleyo ndlela ivimbele ukwakheka kwama-virion asebekhulile.I-Atazanavir ayisebenzi ngokumelene ne-HIV-2.