I-Azilsartan CAS 147403-03-0 Purity >99.5% (HPLC) API Factory
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali | I-Azilsartan |
Omqondofana | 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-Carboxylic Acid |
Inombolo ye-CAS | 147403-03-0 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C25H20N4O5 |
Isisindo samangqamuzana | 456.46 |
I-Melting Point | 188℃ (dec.) |
Ukuminyana | 1.42 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Emhlophe noma Engamhlophe |
Ukuhlonza | Ihambisana Nezinga Lereferensi |
Ukuncibilika | Ayincibiliki Emanzini, Incibilika Kancane ku-Ethanol |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.5% (HPLC) |
Ukulahlekelwa Ekumisweni | <0.50% |
Izinsalela ekushiseni | <0.20% |
Izinsimbi Ezisindayo | <10ppm |
Izinto Ezihlobene | |
Ukungcola A | <0.15% |
Ukungcola B | <0.10% |
Ukungcola C | <0.10% |
Okunye Ukungcola Okukodwa Okukhulu Okungaziwa | <0.10% |
Ukungcola Okuphelele | <0.50% |
Izincibilikisi Ezisele | |
I-Dichloromethane | <0.06% |
I-acetone | <0.50% |
I-Ethyl Acetate | <0.50% |
I-Methanol | <0.30% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-API |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-Azilsartan (i-CAS: 147403-03-0) iyisidakamizwa esiphikisana nesamukeli se-angiotensin II esathuthukiswa ukwelapha umfutho wegazi ophakeme, osetshenziswa kakhulu ekwelapheni umfutho wegazi ophakeme.Futhi ukuphela kwesidakamizwa esimelana ne-angiotensin II receptor antagonist (isigaba se-sartan) esisesigabeni somtholampilo esithuthukisiwe njengamanje.Inhlanganisela ye-Azilsartan neChlorthalidone isetshenziselwa ukwelapha umfutho wegazi ophakeme (hypertension).I-Azilsartan iyi-angiotensin II receptor blocker (ARB).Isebenza ngokuvimba into ethile emzimbeni eyenza imithambo yegazi iqine.Ngenxa yalokho, i-azilsartan ikhulula imithambo yegazi.Lokhu kwehlisa umfutho wegazi futhi kwandisa ukuhlinzekwa kwegazi nomoya-mpilo enhliziyweni.I-Azilsartan yavunywa futhi yethulwa e-Japan ukuze zelashwe i-arterial hypertension ngo-May 2012. I-Azilsartan, ethengiswa ngaphansi kwegama lokuhweba elithi Azilva.