I-Azithromycin Dihydrate CAS 117772-70-0 Assay 945~1030μg/mg API Factory High Quality
Nikeza Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Azithromycin Dihydrate
I-CAS: 117772-70-0
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
| Igama Lekhemikhali | I-Azithromycin Dihydrate |
| Inombolo ye-CAS | 117772-70-0 |
| Inombolo yeCAT | I-RF-API95 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C38H72N2O12 |
| Isisindo samangqamuzana | 748.99 |
| I-Melting Point | 126℃ |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Emhlophe Kuya Kucishe Emhlophe |
| Ukuncibilika | Incibilika ngokukhululekile ku-Anhydrous Ethanol naku-Methylene Chloride, Ayincibiliki Emanzini |
| Ukuhlonza i-IR/HPLC | Ihambisana nezinga lokubhekisela ku-Azithromycin |
| I-Crystallinity | Ihlangabezana Nezimfuneko |
| pH | 9.0~11.0 |
| I-Specific Optical Rotation | -45.0°~-49.0° |
| Izinsimbi Ezisindayo | ≤20ppm |
| Amanzi | 4.0~5.0% |
| Izinsalela ekushiseni | ≤0.20% |
| Izinto Ezihlobene | |
| I-Azithromycin-N-oxide | ≤0.50% |
| 3'-(NN-Didemethyl)Azithromycin(aminozaithromycin) | ≤0.50% |
| I-Azithromycin Inhlanganisela Ehlobene F | ≤0.50% |
| I-Desosaminylazithromycin | ≤0.30% |
| I-N-Demethylazithromycin | ≤0.70% |
| I-Azithromycin-C | ≤0.50% |
| 3'-De(dimethylamino)-3'-oxoazithromycin | ≤0.50% |
| Azaerythromycin A | ≤0.50% |
| I-Azithromycin Impurity P | ≤0.20% |
| 2-Desethyl-2-Propylazithromycin | ≤0.50% |
| 3'-N-DemETHYL-3'n-[(4-methylphenyl)sulfonyl]Azithromycin | ≤0.50% |
| I-Azithromycin-B | ≤1.0% |
| Noma Ikuphi Ukungcola Okungashiwongo | ≤0.20% |
| Ukungcola Okuphelele | ≤3.0% |
| Izincibilikisi Ezisele | |
| I-Methanol | ≤0.30% |
| I-Ethanol | ≤0.05% |
| I-acetone | ≤0.50% |
| I-Chloroform | ≤0.006% |
| Isivivinyo | 945~1030μg/mg (C38H72N2O12 kusisekelo se-anhydrous) |
| I-Shelf Life | Izinyanga ezingama-24 |
| Izinga Lokuhlola | I-USP Standard |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Azithromycin iyimithi elwa namagciwane ene-spectrum ebanzi ye-macrolide enesigamu sempilo ende kanye nezinga eliphezulu lokungena kwezicubu 3. Yagunyazwa ekuqaleni yi-FDA ngo-1991. Isetshenziselwa kakhulu ukwelapha izifo zokuphefumula, ze-enteric kanye ne-genitourinary futhi ingaba esetshenziswa esikhundleni sama-macrolide kwezinye izifo ezithathelwana ngocansi kanye ne-enteric.Ihlobene nesakhiwo ne-erythromycin.I-Azithromycin ivimbela amagciwane ekukhuleni ngokuphazamisa ukwakheka kwawo kwamaprotheni.Ibophezela ku-50S subunit ye-ribosome yebhaktheriya, ngaleyo ndlela ivimbele ukuhunyushwa kwe-mRNA.I-Nucleic acid synthesis ayithinteki.
