I-Betulin CAS 473-98-3 Purity >99.0% (HPLC) Isizinda Sesitshalo
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Betulin (CAS: 473-98-3) enekhwalithi ephezulu.I-Ruifu Chemical ingahlinzeka ngokulethwa komhlaba wonke, amanani ancintisanayo, amanani amancane nayinqwaba atholakalayo.Thenga i-Betulin,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | Betulin |
| Omqondofana | I-Betulinol;I-Betulinic Alcohol;Betula Camphor;I-Birch Bark Extract;I-Betulol;I-Trochol;I-Lup-20(29)-ene-3β,28-diol;(3β)-Lup-20(29)-ene-3,28-diol |
| Isimo Sesitoko | Esitokweni, Kwenzelwe Ukuthengisa |
| Inombolo ye-CAS | 473-98-3 |
| I-Molecular Formula | I-C30H50O2 |
| Isisindo samangqamuzana | 442.73 g/mol |
| I-Melting Point | 251.0~257.0℃ |
| Ukuminyana | 1.017g/cm3 |
| Ukuzungezisa Okuthile [a]20/D | +17.0° ukuya +21.0° (C=2 ku-Pyridine) |
| Ukuzinza | I-Hygroscopic |
| Isikhathi Sokugcina. | Indawo epholile neyomile (2~8℃) |
| I-COA ne-MSDS | Iyatholakala |
| Isigaba | Izingcaphuno Zezitshalo |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | Impushana Emhlophe Kuya Kumhlophe | Impushana Emhlophe |
| I-Betulin Purity | >98.0% (HPLC) | 99.15% |
| I-Melting Point | 251.0~257.0℃ | Iyahambisana |
| Ukulahlekelwa Ekumisweni | <2.00% (2g/105℃/5hrs) | 0.13% |
| Umlotha | <0.50% (2g/600℃/5hrs) | 0.10% |
| Ukuminyana kwenqwaba | 0.25~0.45 g/ml | Iyahambisana |
| Usayizi Wezinhlayiyana | 98% Dlula i-80 Mesh | Iyahambisana |
| Izinsimbi Ezisindayo (Pb) | ≤10ppm | <10ppm |
| I-Arsenic (As) | ≤1ppm | <1ppm |
| I-Residual Solvent | ≤1000ppm | Iyahambisana |
| Ukuhlolwa kweMicrobiological | ||
| Inani Lepuleti Eliphelele | ≤1000CFU/g | Iyahambisana |
| Imvubelo & Isikhunta | ≤100CFU/g | Iyahambisana |
| Escherichia Coli | Okubi | Okubi |
| I-Infrared Spectrum | Ivumelana Nesakhiwo | Iyahambisana |
| I-Solubility ku-Pyridine 50mg/ml | Okuphuzi ukuya ku-Brown Kucace kuya ku-Slighty Hazy | Dlula |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nezicaciso | |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina esitsheni esivalwe ngci.Gcina endaweni epholile, eyomile (2~8℃) futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama kanye nezinga lokushisa eliphezulu.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Amakhodi Engozi
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
R20/21/22 - Kuyingozi ngokuhogela, ukuthintana nesikhumba futhi uma ukugwinyile.
R68/20/21/22 -
I-R68 - Ingozi engaba khona yemiphumela engenakuhlehliswa
Incazelo Yokuphepha
I-S36/37 - Gqoka izingubo zokuzivikela ezifanele namagilavu.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-WGK Germany 3
I-RTECS OK5755000
I-HS Code 2906199090
I-Betulin (i-CAS: 473-98-3) ikhishwe egxolweni lesihlahla se-birch esimhlophe, elaziwa kusukela ngekhulu le-18 futhi lichazwa ngamakhemikhali.I-Betulin yatholwa usokhemisi waseJalimane-Russian u-Johann Tobias Lowitz.Wayengusosayensi wokuqala ukufunda nokuchaza i-betulin, futhi ngokwenza kwakhe kwaba ngomunye wabokuqala ukuhlukanisa isithako sesitshalo esisebenzayo.I-Betulin iwumthombo wesitshalo omsulwa onikeza igxolo le-birch umbala walo omhlophe ojwayelekile.I-Betulin ivikela izihlahla ze-birch emiphumeleni yemvelo, njengamazinga okushisa aphezulu, ukuhlasela kwezinambuzane kanye nemisebe yelanga.
I-Betulin iyimpushana emhlophe e-crystalline, encibilika otshwaleni, i-chloroform ne-benzene, incibilika kancane emanzini abandayo, i-petroleum ether.
Imiphumela ye-physiological ye-betulin
1. I-Betulin kanye nokuphuma kwayo kubonise amandla amakhulu njengama-biological agents ekwelashweni kwe-HIV nomdlavuza.Asebenza ngokuphazamisa izigaba zakamuva zomjikelezo wempilo yegciwane futhi ahlobene nokungena kwegciwane nokukhula nokuvuthwa.
2. Izidakamizwa eziphumelelayo zokulwa nesimila, ezibangela ngokuqondile ukuthi ezinye izinhlobo zamangqamuzana e-tumor ziqalise izinhlelo ezizilimazayo ze-apoptosis, futhi zingabambezela ukukhula kwezinhlobo ezimbalwa zamaseli wesimila.
3. I-Betulin inganciphisa ukukhuluphala okubangelwa ukudla, inciphise okuqukethwe kwe-lipid ku-serum nezicubu, futhi ithuthukise ukuzwela kwe-sulin k.
4. Banezakhiwo ezincane zokulwa nokuvuvukala ezindaweni eziphezulu, futhi izakhiwo zabo zokulwa nokuvuvukala zibangelwa ikakhulukazi ukuvinjelwa kwezindlela zofuzo ezingezona ze-neural.
5. I-Betulin ingavimbela ukuvuthwa kwe-sterol regulatory element-binding proteins (SBERPs) ku-vivo, ngaleyo ndlela yehlise i-biosynthesis ye-cholesterol nama-fatty acids.
6. Ngaphezu kwalokho, i-Betulin ine-anti-inflammatory, anti-viral, inhibiting protein dissolution in hair fiber, ithuthukisa ukucwebezela kwezinwele ezilimele, futhi ikhuthaze ukukhula kwezinwele.I-Betulin ingasetshenziswa ezimbonini zokudla, izimonyo nezithakazelo zemithi.
Imboni yezemithi:
I-Betulin isetshenziswa kakhulu njengendawo emaphakathi yemithi, futhi i-Betulin kanye nokuphuma kwayo njengama-ejenti ebhayoloji ibonise amandla amakhulu ekwelapheni i-HIV nomdlavuza.Ngesikhathi esifanayo, isetshenziselwa i-antitussive ne-expectorant, ukwelashwa kwe-rhinitis ye-allergen, ukuqwasha, ukucindezeleka, njll.
Imboni Yokudla:
Kukhona izifundo eziyisebenzisa njengesilondolozi emikhiqizweni yenyama.
Imboni yezimonyo:
Umphumela ovimbelayo we-Betulin emsebenzini we-collagenase nokwanda kwamangqamuzana esikhumba ubonisa ukuthi unomphumela oqinile wokulwa nokuguga futhi ungasetshenziswa ukulungisa isikhumba, ukushelela isikhumba, nokuvimbela isikhumba esiqhekekile.Kuphinde kube usizo oluhle lokungena ngaphandle.
Njengamanje i-Betulin itholakala ikakhulukazi ngokukhipha okuqondile, futhi ikakhulukazi ngokukhipha i-solvent reflux kanye nokuhlanzwa kabusha kwe-recrystallization Ngokuqondile: 1. Khipha i-betulin kusixazululo se-ethanol.Ngemuva kokushisisa i-reflux cishe amahora angu-5, okukhishiwe kuyakhishwa futhi kufakwe kabusha nge-ethanol izikhathi ezingu-2 kuya kwezi-3 nge-ethanol ukuze kutholwe umkhiqizo ongahluziwe we-betulin.2. Umkhiqizo ongahluziwe waphinde wahlungwa usuka ku-methanol/chloroform (1: 1) (wonke umkhiqizo ongahluziwe ongu-80g udinga isixazululo se-methanol/chloroform esingu-300mL). Le ngxube ivunyelwa ukuba ime ubusuku bonke bese iyahlungwa ukuze kutholakale i-betulin emhlophe efana nenaliti.3. Ukwelashwa kwe-Ultrasonic kwe-20min lapho i-refluxing yenziwa, futhi isivuno sokukhipha kanye nokuhlanzeka komkhiqizo we-betulin kungathuthukiswa ngokubhujiswa kwenhlangano yamagxolo.4. Izimo ezikahle zokukhishwa koketshezi lwe-CO2 okungaphezu kokubaluleke kakhulu zimi kanje: inani lesilungisi lalingu-115mL/(g igxolo le-birch);ingcindezi yokukhipha ingu-20MPa;izinga lokushisa lokukhipha lalingu-55 ℃;izinga lokugeleza kwe-CO2 eliwuketshezi lalingu-10kg/h.
