I-Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Advanced Prostate Cancer Isithombe Esifakiwe

I-Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Prostate Cancer

Incazelo emfushane:

Igama: Bicalutamide

I-CAS: 90357-06-5

Ukubukeka: I-Crystalline Powder Emhlophe ukuya Kokumhlophe

Isilinganiso: 98.0%~102.0%

I-Bicalutamide ekwelapheni I-Advanced Prostate Cancer

Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Inquiry: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Ukunikezela Komkhiqizi Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama: Bicalutamide
I-CAS: 90357-06-5
I-Bicalutamide ekwelapheni I-Advanced Prostate Cancer
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Chemical Properties:

Igama	I-Bicalutamide
Omqondofana	N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide
Inombolo ye-CAS	90357-06-5
Inombolo yeCAT	I-RF-API76
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu
I-Molecular Formula	I-C18H14F4N2O4S
Isisindo samangqamuzana	430.37
Izinga Lokushisa Lesitoreji	2-8℃
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder emhlophe ukuya kokumhlophe
Ukuhlonza A	IR: I-Spectrum yesampula ihambisana naleyo yezinga lokubhekisela
Ukuhlonza B	I-HPLC: Isikhathi sokugcina sesiqongo esikhulu sesixazululo sesampula sihambisana naleso sesixazululo esijwayelekile
Ukuhlonza C	I-Organic Fluoride Identification
Ukuncibilika	I-Soluble Ngokukhululekile ku-Acetone ne-Tetrahydrofuran, Incibilika Kancane ku-Ethyl Acetate
I-Melting Point	191.0 ~ 195.0℃
Okuqukethwe kwamanzi (nge-KF)	≤0.20%
Okuqukethwe kweFluoride	15.9%~18.5%
Ukulahlekelwa Ekumisweni	≤0.50%
Izinsalela ekushiseni	≤0.10%
Izinsimbi Ezisindayo	≤10ppm
Izincibilikisi Ezisele
I-Tetrahydrofuran	≤0.072%
I-Toluene	≤0.089%
N-Hexane	≤0.029%
I-acetone	≤0.50%
I-Ethyl Acetate	≤0.50%
Izinto Ezihlobene
N,N'-Dimethyl Acetamide	≤0.109%
I-Bicalutamide Aminobenzonitrile	≤0.10%
I-Bicalutamide Inhlanganisela Ehlobene A Isomer A	≤0.10%
I-Bicalutamide Inhlanganisela Ehlobene A Isomer B	≤0.10%
I-Desfluoro Bicalutamide	≤0.20%
2-Fluoro Bicalutamide	≤0.20%
I-Deoxy Bicalutamide	≤0.20%
I-Bicalutamide sulfide	≤0.10%
Noma Ikuphi Ukungcola Okungashiwongo	≤0.10%
Ukungcola Okuphelele	≤0.50%
Usayizi Wezinhlayiyana	90%<10um;50%<5um
Isivivinyo	98.0% ~ 102.0% (komisiwe)
Ukuhlolwa kweMicrobiological
Isamba Sesibalo Se-Aerobic Esisebenzayo	≤500CFU/g
Imvubelo kanye Nesikhunta	≤50CFU/g
I-Shelf Life	Izinyanga ezingama-24
Izinga Lokuhlola	Izinga lebhizinisi;I-USP Standard
Ukusetshenziswa	I-API, ekwelapheni I-Advanced Prostate Cancer

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-Bicalutamide (i-CAS: 90357-06-5) iwumphikisi we-androgen ongeyona i-steroidal, eqhudelana ne-androgen receptor ne-androgen, ivimbele ukutholwa kwamaselula kwe-androgen, futhi ivimbele ukubopha kwama-androgens esithweni esihlosiwe.Ibophezela ne-androgen receptor eyenza i-receptor complex, engena ku-nucleus futhi ihlanganiswe ne-nucleoprotein, ngenxa yalokho ivimbela ukukhula kweseli yesimila.Kungaba njengomuthi womugqa wokuqala wokwelapha okudambisa umdlavuza wendlala yesinye osethuthukile.I-Bicalutamide yethulwa e-United Kingdom, imakethe yayo yokuqala emhlabeni wonke, yokwelapha umdlavuza wendlala yesinye osethuthukile kuhlanganiswe ne-analog ye-LHRH noma ukuthenwa ngokuhlinzwa.I-non-steroidal, i-peripherally selective antiandrogen, i-bicalutamide ivimbela isenzo se-dihydrotestosterone kanye ne-testosterone kumasayithi okuhlosiwe ngokubophezela ngokuncintisana ku-cytosolic androgen receptor.Kubikwa ukuthi kubekezelelwe kahle ngaphandle kwemiphumela emibi yenhliziyo nemithambo yegazi ngenxa yenzuzo yokuntula noma yimuphi umsebenzi we-steroid.Ukusebenza kwe-bicalutamide njenge-monotherapy kuye kwaboniswa emtholampilo.Amazinga okuphendula athembisayo nawo abikwa ekwelapheni umdlavuza wamaphaphu we-colorectal, webele, wamanyikwe kanye nongewona omncane.