I-Biotin CAS 58-85-5 Assay 97.5~100.5% Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Biotin (Vitamin H) (CAS: 58-85-5) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Biotin (CAS: 58-85-5),Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-Biotin |
| Omqondofana | I-D-Biotin;D(+)-Biotin;Vitamin H;I-Bios II;I-Vitamin B7;I-Coenzyme R;I-Biotinum |
| Isimo Sesitoko | Ku-Stock, Commercial Production |
| Inombolo ye-CAS | 58-85-5 |
| I-Molecular Formula | I-C10H16N2O3S |
| Isisindo samangqamuzana | 244.31 g/mol |
| I-Melting Point | 231.0~233.0℃(lit.) |
| Ukuncibilika kwamanzi | Incibilika Kancane Emanzini |
| Ukuncibilika ku-0.1mol/L NaOH | Cishe Ukungafihli |
| Ukuncibilika | Incibilika Kancane Otshwaleni, I-Chloroform, i-Ether |
| I-COA ne-MSDS | Iyatholakala |
| Umsuka | Shanghai, China |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | I-Crystalline Powder Emhlophe noma Cishe Emhlophe | I-Crystalline Powder Emhlophe |
| Ukuhlonza | I-IR Match ne-Reference IR Spectrum | Iyahambisana |
| Isikhathi Sokugcina | Kufanele ifane neye-RS | Iyahambisana |
| Ukuzungezisa Okuthile [a]20/D | +89.0° ukuya +93.0° (C=2 ku-0.1 M NaOH) | +90.8° |
| Isivivinyo | 97.5~100.5% | 99.8% |
| Ukulahlekelwa Ekumisweni | <0.50% | 0.05% |
| Izinto Ezihlobene | ||
| Ukungcola Ngamunye | <1.00% | Iyahambisana |
| Ukungcola Okuphelele | <2.00% | Iyahambisana |
| Izincibilikisi Ezisele | ||
| Benzeni | <2ppm | <0.2ppm |
| I-Toluene | <100ppm | <10ppm |
| I-DMSO | <5000ppm | <500ppm |
| Ukuhlolwa kwe-Microbial | ||
| Isamba Sesibalo Se-Aerobic Esisebenzayo | ≤1000cfu/g | Iyahambisana |
| Isamba Semvubelo Nesikhunta Sibala | ≤100cfu/g | Iyahambisana |
| Escherichia Coli | ND/1g | / |
| I-Staphylococcus Aureus | ND/1g | / |
| I-Pseudomonas Aeruginosa | ND/1g | / |
| I-Enterobacteria | ND/1g | / |
| Izinhlobo ze-Salmonella | ND/10g | / |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isiqukathi sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile (2~8℃) nengena umoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
INCAZELO Ukuhlaziya I-Biotin iqukethe i-NLT 97.5% kanye ne-NMT 100.5% ye-Biotin (C10H16N2O3S).
UKUKHOMBA
• A. UKUMUMVA OKUNOMTHWALO <197K>
B. Ihlangabezana nezimfuneko Ekuhloleni Okuqondile Kokuzungezisa Kwamehlo, Ukuzungezisa Okuthile <781S>.
C. Isikhathi sokugcina sesiqongo esikhulu sesixazululo Sesampuli sihambisana naleso Sesixazululo Esijwayelekile, njengoba sitholwe ku-Assay.
ISIVIVINYO
• INQUBO
Isixazululo se-buffer: Chaza i-1 g ye-sodium perchlorate monohydrate ku-500 mL wamanzi, engeza i-1 mL ye-phosphoric acid, bese uhlanza ngamanzi ku-1000 mL.
Isigaba seselula: Isixazululo se-Acetonitrile ne-Buffer (8.5: 91.5)
I-Diluent: I-acetonitrile namanzi (1:4)
Isixazululo esijwayelekile: 0.1 mg/mL ye-USP Biotin RS ku-Diluent.I-Sonicate uma kunesidingo ukuze ichithe
Isixazululo sesampula: 0.1 mg/mL ye-Biotin ku-Diluent.I-Sonicate uma kunesidingo ukuze ichithe.
Isistimu yeChromatographic
(Bona i-Chromatography <621>, Ukufaneleka Kwesistimu.)
Imodi: LC
Umtshina: UV 200 nm
Ikholomu: 4.6-mm × 15-cm;3-µm ukupakisha L7
Izinga lokugeleza: 1.2 mL/min
Usayizi womjovo: 50 µL
Ukufaneleka kwesistimu
Isampula: Isixazululo esijwayelekile
Izidingo zokufaneleka
Isici somsila: NMT 1.5
Ukuchezuka okujwayelekile okuhlobene: I-NMT 2.0% yemijovo eyimpinda
Ukuhlaziya
Amasampula: Isixazululo esijwayelekile kanye nesixazululo esiyisampula
Bala iphesenti le-Biotin (C10H16N2O3S) engxenyeni ye-Biotin ethathiwe:
Umphumela = (rU/rS) × (CS/CU) × 100
rU = impendulo ephezulu evela kusixazululo Sesampula
rS = impendulo ephezulu evela kusixazululo Esijwayelekile
CS = ukugxila kwe-USP Biotin RS kusixazululo Esijwayelekile (mg/mL)
CU = ukugcwala kwe-Biotin kusixazululo Sesampula (mg/mL)
Indlela yokwamukela: 97.5% -100.5%
UKUNGCOLA
• AMACOMPOUND ESIPHATHELENE
Isixazululo se-buffer, isigaba seselula, i-Diluent, isixazululo esijwayelekile, isixazululo sesampuli, isistimu ye-Chromatographic nokufaneleka kwesistimu: Qhubeka njengoba uqondiswe ku-Assay.
Ukuhlaziya
Isampula: Isixazululo sesampula
Linganisa izimpendulo eziphezulu zesixazululo Sesampuli.
Bala iphesenti lokungcola ngakunye engxenyeni ye-Biotin ethathiwe:
Umphumela = (rU/rT) × 100
i-rU = impendulo ephakeme kakhulu yokungcola ngakunye okuvela kusixazululo Sesampula
rT = isamba sezimpendulo eziphakeme zazo zonke iziqongo ezivela kusixazululo Sesampula
Imibandela yokwamukela
Ukungcola komuntu ngamunye: NMT 1.0%
Ukungcola okuphelele: NMT 2.0%
IZIVIVINYO EZITHILE
• UKUZUNGUZA KWE-OPTICAL, Ukuzungezisa Okuqondile <781S>
Isixazululo sesampula: 20 mg/mL ku-0.1 N sodium hydroxide
Imibandela yokwamukela: +89° ukuze +93°
IZIDINGO EZENGEZIWE
• UKUPAKASHA KANYE NESIGCINI: Gcina ezitsheni eziqinile.
• AMAZINGA EREferensi e-USP <11>
USP Biotin RS
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Izimpawu Zengozi Xn - Ziyingozi
Amakhodi Engozi R20/21/22 - Kuyingozi ngokuhogela umoya, ukuthinta isikhumba futhi uma ukugwinyile.
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yezokuphepha S24/25 - Gwema ukuthintana nesikhumba namehlo.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-WGK Germany 1
I-RTECS XJ9088200
I-FLUKA BRAND F AMAKHODI 8
TSCA Yebo
I-HS Code 2936290000
Ubuthi LD50 ngomlomo kuNogwaja: > 2000 mg/kg
I-Biotin (I-Vitamin H; I-Vitamin B7) (CAS: 58-85-5)
I-Biotin iyivithamini encibilikayo emanzini ngezindlela eziyisishiyagalombili, i-biotin.Kuyi-coenzyme - noma i-enzyme yomsizi - esetshenziswa ekuphenduleni okuningi kwe-metabolic emzimbeni.I-Dchemicalbook-biotin ibandakanyeka ku-lipid ne-protein metabolism, isiza ukuguqula ukudla kube ushukela, umzimba ongawusebenzisa njengamandla.Kubalulekile futhi ekugcineni isikhumba, izinwele kanye nolwelwesi lwamafinyila.
Njengesengezo sokuphakelayo, i-Biotin isetshenziselwa ikakhulukazi izinkukhu nokudla kokuhlwanyela.Ngokuvamile ingxenyana yenqwaba exutshiwe iba ngu-1% -2%.
I-Biotin iyisengezo sokudla okunempilo.Ngokusho kwemithetho yaseChina GB2760-90, ingasetshenziswa njengemboni yokudla njengosizo lokucubungula.Inemisebenzi yomzimba yokuvikela izifo zesikhumba futhi ikhuthaze i-lipid metabolism nokunye.
I-Biotin iyi-coenzyme ye-carboxylase, ebandakanyeka ekuphenduleni okuningi kwe-carboxylation, futhi iyi-coenzyme ebalulekile kumetabolism kashukela, amaprotheni namafutha.
I-Biotin isetshenziswa njengokuqinisa ukudla.I-Biotin isetshenziselwa ukudla kwezingane ezinenani elingu-0.1~0.4mg/kg, oketshezini oluphuzwayo 0.02~0.08mg/kg.
I-Biotin ingasetshenziselwa ukulebula amaprotheni, ama-antigen, amasosha omzimba, ama-nucleic acid (DNA, RNA) nokunye.
I-Biotin ingenza izinwele zinwebeka, ivimbele ukulahleka kwezinwele kusenesikhathi futhi ithuthukise ukumelana kwemvelo kwesikhumba.Iphinde ibe nempumelelo ethile ye-anti-wrinkle.Ingathuthukisa ukwakheka kwenhlangano okuphelele kwesikhumba, yandise ukuguquguquka kwezinzipho, ithuthukise ukwakheka kwezinzipho eziphukayo futhi yenze izinzipho zibe zinhle futhi zibushelelezi ngokukhuthaza ukwakheka kwe-lipids.
Ukungabikho kwe-biotin kungase kubangele i-dermatitis, i-atrophic glossitis, i-hyperesthesia, i-myalgia, i-malaise, i-anorexia, ne-anemia encane, futhi izimpawu zinyamalale ngokufaka i-biotin.Umphumela wayo ovame kakhulu ukuqubuka kwe-cystic acne.Kodwa kubantu abaningi, ngisho nokusetshenziswa ngokweqile kwale vithamini akubangeli umphumela omubi.Kodwa-ke, abesifazane abakhulelwe akufanele bathathe i-biotin ngenxa yengozi yokukhulelwa kwesisu.
Ubuthi be-Biotin bubonakala buphansi, ukwelashwa kwe-seborrheic dermatitis ngemithamo ephezulu ye-Biotin akuzange kuveze okungavamile kwamaprotheni metabolism noma amaphutha ofuzo nokunye ukuphazamiseka kwe-metabolic.Ukuhlolwa kwezilwane nakho kubonise ubuthi obuncane be-Biotin.
