I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Purity ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Intermediate
Thola Izimo Ezihlobene Ne-Sitagliptin Phosphate Monohydrate:
I-Sitagliptin API CAS 486460-32-6
I-Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6
I-Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Igama Lekhemikhali | I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid |
Omqondofana | (R)-Sitagliptin N-Boc-Acid Ukungcola |
Inombolo ye-CAS | 486460-00-8 |
Inombolo yeCAT | I-RF-PI1192 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C15H18F3NO4 |
Isisindo samangqamuzana | 333.31 |
I-Melting Point | 136.0 ~ 138.0℃ |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe Kuya Kumhlophe |
Ukuhlonza nge-HPLC | Isikhathi Sokugcina Sesampula Sihambisana Nezithenjwa Ezijwayelekile |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Umlotha one-sulphate | ≤0.50% |
Izinsimbi Ezisindayo | <20ppm |
Isomer | ≤0.50% |
Izinto Ezihlobene | |
Ukungcola A | ≤0.50% |
Noma Ikuphi Okunye Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤0.50% |
Ubumsulwa | ≥99.5% (HPLC) |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
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I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) iyisimaphakathi esibalulekile sokulungiswa kwe-sitagliptin.I-Sitagliptinphosphate inhibitor yokuqala ye-dipeptidase -IV(DPP-4) egunyazwe yi-FDA ngo-2006. Isetshenziselwa ukwelapha uhlobo lwesifo sikashukela sohlobo lwesibili.Inomphumela osobala we-hypoglycemic lapho isetshenziswa iyodwa noma ihlanganiswe ne-metformin ne-pioglitazone, futhi iphephile ukuyithatha, ibekezelelwa kahle, nokusabela okumbalwa okungekuhle.Ngo-Agasti 2009, umuthi wagunyazwa yi-European Union njengomuthi womugqa wokuqala wokwelapha isifo sikashukela sohlobo 2.Ngemuva kuka-2011, amazwe ngemva kwamanye agunyaze inhlanganisela ye-sitagliptin phosphate ne-alpha glycosidase inhibitors noma i-insulin.I-Sitagliptin phosphate iyi-inhibitor yokuqala ye-dipeptidyl peptidase-IV egunyazwe yi-FDA ukuthi isetshenziselwe ukwelapha uhlobo 2 sikashukela kuze kube manje, ngaphansi kwegama lokuhweba elithi Januvia.
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I-Sitagliptin CAS 486460-32-6 Ubumsulwa >99.0% (HPLC...
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I-Sitagliptin Phosphate Monohydrate CAS 654671-77...
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2,4,5-Trifluorophenylacetic Acid CAS 209995-38-...
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I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Buty...
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I-Sitagliptin Triazole Hydrochloride CAS 762240-9...
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I-Sitagliptin Phosphate Monohydrate Intermediate ...