I-Brigatinib CAS 1197953-54-0 Ubumsulwa >99.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: Brigatinib

Amazwi afanayo: AP-26113

I-CAS: 1197953-54-0

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: Impushana Emhlophe ukuya Emhlophe

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

1197953-54-0 -Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Brigatinib (AP-26113) (CAS: 1197953-54-0) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Brigatinib,Please contact: alvin@ruifuchem.com

1197953-54-0 -Chemical Properties:

Igama Lekhemikhali	Brigatinib
Omqondofana	I-AP26113;AP-26113;5-Chloro-N4-[2-(Dimethylphosphinyl)phenyl]-N2-[2-Methoxy-4-[4-(4-Methyl-1-Piperazinyl)-1-Piperidinyl]phenyl]-2,4-Pyrimidinediamine
Isimo Sesitoko	Ku-Stock, Commercial Production
Inombolo ye-CAS	1197953-54-0
I-Molecular Formula	I-C29H39ClN7O2P
Isisindo samangqamuzana	584.09 g/mol
I-Melting Point	>203℃(Disemba)
Ukuminyana	1.31±0.10 g/cm3
I-COA ne-MSDS	Iyatholakala
Umsuka	Shanghai, China
Ibhrendi	I-Ruifu Chemical

1197953-54-0 -Imininingwane:

Izinto	Imininingwane	Imiphumela
Ukubukeka	Impushana Emhlophe Kuya Kumhlophe	Iyahambisana
Ukuhlanzeka / Indlela Yokuhlaziya	>99.0% (HPLC)	99.26%
Ubukhulu.Ukungcola Okukodwa	<1.00%	0.25%
Ukulahlekelwa Ekumisweni	<1.00%	0.27%
I-Infrared Spectrum	Ihambisana Nesakhiwo	Iyahambisana
1H NMR Spectrum	Ihambisana Nesakhiwo	Iyahambisana
Isiphetho	Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe

Iphakheji/Isitoreji/Ukuthumela ngomkhumbi:

Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.

Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.

Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.

IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.

Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.

Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.

Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.

1197953-54-0 - Incazelo Ejwayelekile:

I-Brigatinib (AP-26113) (CAS: 1197953-54-0) iwuphenyo lwe-molecule encane eqondiswe ukwelashwa komdlavuza eyenziwa yi-ARIAD Pharmaceuticals, Inc. I-Brigatinib umuthi osetshenziselwa ukwelapha umdlavuza ocindezela i-epidermal growth factor receptor (EGFR) futhi I-anaplastic lymphoma kinase (ALK).I-Brigatinib iyi-agonist ekhethayo emelene nokuhlukahluka kwe-EGFR ngokuphambene namafomu aguqukayo asendle.Umuthi futhi ubonisa ukukhetha ngokumelene nofuzo oluhlanganisiwe lwe-ALK-EML4, okuyingxenye ebalulekile yokuguqulwa kwe-parenchyma yamaphaphu ethintekayo.I-Brigatinib inqunyelwe iziguli ezinezakhi zofuzo ezingavamile futhi lapho umdlavuza wamaphaphu ongewona omncane (NSCLC) ungaphenduli ekuphathweni ngeminye imithi.I-Brigatinib ihlukaniswa njenge-kinase inhibitor, indlela yayo yokusebenza ihlanganisa ukucindezela isenzo samaprotheni angavamile athuthukisa ukuphindaphindeka kwamangqamuzana omdlavuza.

1197953-54-0 - Izinkomba:

I-Brigatinib (i-CAS: i-1197953-54-0) inqunyelwe iziguli ezinezinhlobo ezithile ze-NSCLC eziye zasakazeka ezingxenyeni ezihlukahlukene zomzimba kubantu abaye bathola ukwelashwa kwangaphambili neminye imithi yomdlavuza njenge-Crizotinib, futhi isimo sabo siye saba sibi kakhulu. noma zikhombisa izimpawu zokuthuthuka okuncane.Ikakhulukazi ingaphansi kophenyo ngokwelashwa kwayo kumdlavuza wamaphaphu ongewona omncane (NSCLC) lapho i-ALK icushwa khona futhi uguquko lwe-EGFP luvame ukwenzeka.

1197953-54-0 - Isicelo:

I-Brigatinib (AP-26113) (CAS: 1197953-54-0) iyisivimbeli sesizukulwane esisha se-tyrosine kinase, esibonisa ukusebenza kahle okubalulekile ku-ALK+ metastatic NSCLC.Ngomhla zingama-30 ku-Agasti, i-2016, i-United States FDA inikeze i-bugtinib njengokwelapha okuphumelelayo kanye nomuthi ongajwayelekile we-ALK+NSCLC ezigulini ezithuthuke noma ezingakwazi ukubekezelela i-Crizotinib, ukwelashwa kwe-ALK+NSCLC yesizukulwane sokuqala.Nikeza kuqala ukubuyekezwa kwesicelo sokufakwa ohlwini futhi uvumele idatha yesicelo ukuthi ihanjiswe ngokuqhubekayo.I-FDA igunyaze i-Bugtinib ngo-Ephreli 28, 2017, ngaphansi kwegama lokuhweba elithi Alunbrigtm.