I-Capecitabine CAS 154361-50-9 Purity 98.0%~102.0% API Ikhwalithi Ephezulu
I-Commercial Supply Ehlobene Ne-Capecitabine:
I-5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
I-Capecitabine CAS: 154361-50-9
| Igama Lekhemikhali | Capecitabine |
| Inombolo ye-CAS | 154361-50-9 |
| Inombolo yeCAT | I-RF-API08 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C15H22FN3O6 |
| Isisindo samangqamuzana | 359.35 |
| I-Melting Point | 110.0 ~ 121.0℃ |
| Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Emhlophe |
| Ukuhlonza | Isampula ye-IR Spectrum kufanele ihambisane ne-spectrum yezinga lesithenjwa |
| Ukuhlonza | I-HPLC: Isikhathi sokugcina sesiqongo esikhulu sesixazululo sesampula kufanele sihambisane naleso sezinga lesithenjwa. |
| Ubumsulwa | 98.0%~102.0% (ngesisekelo se-anhydrous ne-solvent-free) |
| Ukujikeleza kwe-Optical | +96.0°~+100° |
| Umswakama (KF) | ≤0.30% |
| Izinsalela ekushiseni | ≤0.10% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Ukungcola Okuhlobene A | ≤0.30% |
| Ukungcola Okuhlobene B | ≤0.30% |
| Ukungcola Okuhlobene C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
| Ukungcola Okukodwa Okungacacisiwe | ≤0.10% |
| Isamba Sokungcola Okungashiwongo | ≤0.50% |
| Ukungcola Okuphelele | ≤1.5% |
| I-Residual Solvents (GC) | |
| I-Methanol | ≤3000ppm |
| I-Ethanol | ≤5000ppm |
| I-Dichloromethane | ≤600ppm |
| I-Ethyl Acetate | ≤5000ppm |
| I-Toluene | ≤800ppm |
| I-Pyridine | ≤200ppm |
| I-Hexane | ≤290ppm |
| Isamba se-Aerobic Microbial Count | ≤200cfc/g |
| Imbiliso Nesikhunta Kubalwa | ≤50cfc/g |
| Izinga Lokuhlola | I-United States Pharmacopoeia (USP) |
| Ukusetshenziswa | I-Metastatic Breast Cancer |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Capecitabine (CAS: 154361-50-9) iwuhlobo olusha lomuthi we-oral fluorinated pyrimidine.I-Capecitabine yasungulwa ngabakwa-Roche Pharmaceuticals, futhi igama layo lezentengiso yi-Xeloda.I-Capecitabine ingashintsha ku-vivo ibe yi-5- FU, isidakamizwa esilwa ne-metabolizim fluorine pyrimidine deoxynucleoside carbamate esiqondise amangqamuzana omdlavuza ukuze avimbele ukuhlukana kwamaseli futhi aphazamise i-RNA kanye nokuhlangana kwamaprotheni.Imiphumela yayo iboshelwe kakhulu ezingeni le-TP enzyme expression in neoplastic tissue kanye ne-DPD enzyme ku-vivo expression.Ifaneleka njengokwelashwa okwengeziwe kweziguli ezinomdlavuza webele oyinhloko noma we-metastatic ezingakaphenduli kuma-antibiotic e-paclitaxel noma i-anthracycline.Njengomuthi wokulwa nomdlavuza, usetshenziswa kakhulu ukwelapha umdlavuza webele osezingeni eliphezulu noma we-metastatic, kanye nokwelapha umdlavuza wamaphaphu ongewona omncane, umdlavuza wamaphaphu, umdlavuza wesinye, umdlavuza wamabele, umdlavuza wekoloni, umdlavuza wesisu, nezinye izimila eziqinile. .
