I-Captopril CAS 62571-86-2 API Factory USP High Quality Anti-Hypertension
Ukunikezela Komkhiqizi Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama leKhemikhali: Captopril
I-CAS: 62571-86-2
I-Angiotensin-Converting Enzyme (ACE) Inhibitor Anti-Hypertension Esebenzayo
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
| Igama Lekhemikhali | I-Captopril |
| Omqondofana | (S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline;(S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline |
| Inombolo ye-CAS | 62571-86-2 |
| Inombolo yeCAT | I-RF-API89 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
| I-Molecular Formula | I-C9H15NO3S |
| Isisindo samangqamuzana | 217.29 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
| Isivivinyo | 98.0%~102.0% (ngokomisiwe) |
| I-Melting Point | 104.0~110.0℃ |
| I-Specific Optical Rotation | -125.0° ukuya ku-134.0° |
| I-Acidity | 7.0~8.0 |
| Ukulahlekelwa Ekumisweni | ≤1.0% |
| Izinsalela ekushiseni | ≤0.10% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Izinto Ezihlobene | |
| I-Captopril Disulfide | ≤1.0% |
| Ukungcola Okungaziwa Okukodwa | ≤0.20% |
| Ukungcola Okuphelele | ≤0.50% |
| Ukungcola Okuguquguqukayo Kwezinto Eziphilayo | Ihlangabezana Nezimfuneko |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | Isetshenziswa njenge-Anti-Hypertension Medicament |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Captopril iyisidakamizwa esicwaningwa kakhulu se-angiotensin-converting enzyme (ACE) inhibitors ephakanyiswe njengomuthi we-antihypertensive.Ivimba i-angiotensin-converting enzyme, ecindezela ukwakheka kwe-angiotensin II futhi ikhulule umphumela wayo we-vasoconstricting emithanjeni ye-arterial kanye ne-venous.Sekukonke ukungezwani kwe-vascular peripheral kuyancipha, okuholela ekwehleni komfutho we-arterial.I-Captopril, kanye namanye ama-inhibitors e-ACE, ikhonjiswe ekwelapheni umfutho wegazi ophakeme, ukwehluleka kwenhliziyo okuhlanganayo, ukungasebenzi kahle kwe-ventricular kwesokunxele ngemuva kwe-infarction ye-myocardial, kanye ne-nephropathy yesifo sikashukela.Ekwelapheni umfutho wegazi ophakeme, i-captopril ithathwa njengokwelashwa okukhethayo, kungaba yodwa noma kuhlanganiswe ne-thiazide diuretic.Ukuncipha komfutho wegazi ngokuyinhloko kudalwe ukwehla kokumelana ne-peripheral noma ukulayishwa ngemva kokulayisha.Inzuzo yokuhlanganisa ukwelashwa kwe-captopril ne-thiazide diuretic evamile ukuthi i-hypokalemia eyenziwa yi-thiazide incishiswa lapho kukhona ukuvinjelwa kwe-ACE, njengoba kunokuncipha okukhulu kokukhululwa kwe-aldosterone kwe-angiotensin II.
