8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS 100331-89-3 Indacaterol Maleate Intermediate Factory

Incazelo emfushane:

8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline

I-CAS: 100331-89-3

Ukubukeka: Okumhlophe Okumhlophe ukuya Kokuphuzi

Ubumsulwa: >95.0% (HPLC)

I-Indacaterol Maleate emaphakathi (CAS: 753498-25-8)

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali 8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline
Omqondofana 8-(Benzyloxy)-5-(2-Bromoacetyl)quinolin-2(1H)-one;5-(Bromoacetyl)-8-(Phenylmethoxy)-2(1H)-Quinolinone;5-(2-Bromo-1-Oxoethyl)-8-Benzyloxy-2(1H)-Quinolinone;I-5-Bromoacetyl-8-Benzyloxycarbostyril
Inombolo ye-CAS 100331-89-3
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Emakhulwini Amakhilogremu
I-Molecular Formula I-C18H14BrNO3
Isisindo samangqamuzana 372.21
I-Melting Point 192.0~194.0℃
Iphuzu elibilayo 602.6±55.0℃ ku-760 mmHg
Ukuminyana 1.479±0.06 g/cm3
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka I-Off-White to Yellow Powder
Ukuhlanzeka / Indlela Yokuhlaziya >95.0% (HPLC)
Umswakama (KF) <1.00%
Izinsalela ekushiseni <0.50%
Ukungcola A <3.00% (5-Acetyl-8-(Benzyloxy)quinolin-2(1H)-one)
Noma Ikuphi Okunye Ukungcola Okukodwa <1.50%
Ukungcola Okuphelele <5.00%
I-Infrared Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Indacaterol Maleate (CAS: 753498-25-8) Phakathi

Iphakheji nesitoreji:

Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
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Izinzuzo:

10

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100331-89-3 - Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline (CAS: 100331-89-3) enekhwalithi ephezulu, imaphakathi ngokuvamile ukuhlanganiswa kwe-Indacaterol Maleate (CAS: 753498-25-8).

I-Indacaterol Maleate (CAS: 753498-25-8) iyinhlangano entsha, esebenza isikhathi eside, eqala ngokushesha i-β (2) -adrenoceptor agonist ne-bronchodilator.Isetshenziswa ekwelapheni isifo esingamahlalakhona se-obstructive pulmonary (COPD) kanye nesifuba somoya.I-European Medicines Agency (EMA) igunyaze i-indacaterol njengomuthi ngo-2009 ngaphansi kwegama lokuhweba le-Onbrez ngenkathi e-United States i-Food and Drug Administration yagunyaza ngaphansi kwegama lokuhweba i-Arcapta ngo-2011.Futhi, i-indacaterol iyi-molecule ye-chiral;nokho, i-R-enantiomer ehlanzekile kuphela esatshalaliswa.

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