4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile CAS 143782-23-4 Enzalutamide Intermediate Purity >98.0% (GC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile (CAS: 143782-23-4) enekhwalithi ephezulu, emaphakathi ye-Enzalutamide (CAS: 915087-33-1).I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Enzalutamide Intermediates,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | 4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile |
| Omqondofana | 4-Cyano-3-(Trifluoromethyl)phenyl Isothiocyanate;I-Isothiocyanic Acid 4-Cyano-3-(Trifluoromethyl)phenyl Ester;4-Isothiocyanato-2-Trifluoromethylbenzonitrile;3-Fluoro-4-Methylphenylisothiocyanate |
| Isimo Sesitoko | Ku-Stock, Commercial Production |
| Inombolo ye-CAS | 143782-23-4 |
| I-Molecular Formula | I-C9H3F3N2S |
| Isisindo samangqamuzana | 228.19 g/mol |
| I-Melting Point | 39.0 ukuze 43.0℃ |
| Iphuzu elibilayo | 331℃ |
| I-Flash Point | 154℃ |
| Ukuminyana | 1.31 |
| Kuyazwela | Kuyazwela Umswakama, Kuyazwela Ukushisa |
| I-COA ne-MSDS | Iyatholakala |
| Isampula | Iyatholakala |
| Umsuka | Shanghai, China |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | I-Off-White Powder | I-Off-White Powder |
| I-Melting Point | 39.0 ukuze 43.0℃ | 41.2℃ |
| Ukulahlekelwa Ekumisweni | <0.50% | 0.19% |
| Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) | 98.8% |
| I-Infrared Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| 1H NMR Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
| Isicelo | I-Enzalutamide emaphakathi (CAS: 915087-33-1) | |
Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isiqukathi sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile (2~8℃) nengena umoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-H302 + H312 + H332: Iyingozi uma igwinywe, ithinta isikhumba noma uma ihogeliwe.
I-H315: Ibangela ukucasuka kwesikhumba.
I-H319: Ibangela ukucasuka kwamehlo okukhulu.
I-H335: Ingabangela ukucasuka kokuphefumula.
I-P501: Lahla okuqukethwe/isiqukathi endaweni egunyaziwe yokulahla udoti.
P261: Gwema ukuphefumula uthuli/ intuthu/ igesi/ inkungu/ umhwamuko/ isifutho.
I-P270: Ungadli, ungaphuzi noma ubheme lapho usebenzisa lo mkhiqizo.
P271: Sebenzisa ngaphandle kuphela noma endaweni engenawo umoya.
I-P264: Geza isikhumba kahle ngemva kokuphatha.
I-P280: Gqoka amagilavu okuzivikela/ izingubo zokuzivikela/ ukuvikela iso/ ukuvikela ubuso.
P337 + P313: Uma ukucasuka kwamehlo kuqhubeka: Thola iseluleko sezokwelapha/ukunakekelwa.
P305 + P351 + P338: UMA EMEHLWENI: Hlanza ngokucophelela ngamanzi imizuzu embalwa.Susa amalensi oxhumana naye, uma ekhona futhi kulula ukuwenza.Qhubeka uhlanza.
I-P332 + P313: Uma ukuluma kwesikhumba kwenzeka: Thola iseluleko sezokwelapha/ukunakekelwa.
I-P362: Khumula izingubo ezingcolile bese ugeza ngaphambi kokuphinda usetshenziswe.
I-P301 + P312 + P330: UMA IGINWE: Shayela I-POISON CENTER/udokotela uma uzizwa ungaphilile.Hlanza umlomo.
P302 + P352 + P312: UMA ESESIKHUmbeni: Geza ngamanzi amaningi.Shayela I-POISON CENTRE/udokotela uma uzizwa ungaphilile.
I-P304 + P340 + P312: UMA UBHOVA: Khipha umuntu emoyeni omusha futhi uhlale unethezekile ukuze uphefumule.Shayela I-POISON CENTER/udokotela uma uzizwa ungaphilile.
I-P403 + P233: Gcina endaweni enomoya omuhle.Gcina isiqukathi sivalwe ngokuqinile.
P405: Isitolo sivaliwe.
I-4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile (CAS: 143782-23-4) isetshenziswa njengendawo ephakathi ye-Enzalutamide (CAS: 915087-33-1).I-Enzalutamide (XTANDI) iphikisana ne-androgen receptor yomlomo, egunyazwe ucwaningo lwamanje lomtholampilo kanye ne-US FDA (Food and Drug Administration), ukuze kuthuthukiswe ukubekezelelwa kwe-post-chemotherapy kwe-metastatic castration yokwelashwa komdlavuza wendlala yesinye (okungukuthi iziguli ezinomdlavuza wendlala yesinye. ngemva kokwelashwa ngamakhemikhali, umdlavuza noma amangqamuzana omdlavuza asakhula ezigulini ezinjalo), anganweba ukusinda kweziguli.Ngo-Agasti 2012, i-FDA yase-US yagunyaza i- enzalutamide yokwelashwa komdlavuza wendlala yesinye we-metastatic castration-resistant (mCRPC) ezigulini ezake zelashwa ngaphambiliniI-Docetaxel.
