I-Lesinurad Intermediate CAS 1533519-84-4 Purity >99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione (CAS: 1533519-84-4) ngekhwalithi ephezulu, ephakathi kweLesinurad (CAS: 878672-00-5).I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Lesnurad Intermediates,Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione |
Omqondofana | 4-(4-Cyclopropylnaphthalen-1-yl) -4H-1,2,4-Triazole-3-Thiol;4-(4-Cyclopropyl-1-Naphthalenyl) -2,4-Dihydro-3H-1,2,4-Triazole-3-Thione;Lesinurad INT3;Lesinurad Ukungcola 20 |
Isimo Sesitoko | Ku-Stock, Commercial Production |
Inombolo ye-CAS | 1533519-84-4 |
I-Molecular Formula | I-C15H13N3S |
Isisindo samangqamuzana | 267.35 g/mol |
Iphuzu elibilayo | 435.2±38.0℃ |
Ukuminyana | 1.41±0.10 g/cm3 |
I-COA ne-MSDS | Iyatholakala |
Umsuka | Shanghai, China |
Isigaba | I-Intermediate of Lesinurad (CAS: 878672-00-5) |
Ibhrendi | I-Ruifu Chemical |
Izinto | Amazinga Wokuhlola | Imiphumela |
Ukubukeka | I-Off-White Powder | I-Off-White Powder |
Amanzi nguKarl Fischer | <0.50% | 0.10% |
Ukulahlekelwa Ekumisweni | <0.50% | 0.40% |
Izinsalela ekushiseni | <0.50% | 0.15% |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) | 99.8% |
I-Infrared Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
1H NMR Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nemibandela enikeziwe |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isiqukathi sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile (2~8℃) nengena umoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-L-Phenylalanine (H-Phe-OH) (i-CAS: 63-91-2) isetshenziswa njengendawo ephakathi ekuhlanganiseni kweLesinurad (CAS: 878672-00-5).I-Lesinurad iyi-inhibitor ekhethiwe ye-uric acid reabsorption esetshenziswa ngokuhlangana namanye ama-ejenti ekwelapheni i-gout.I-Lesinurad (igama lomkhiqizo i-Zurampic) iyisivimbeli sokuqala esikhethiwe se-uric acid reabsorption (SURI) esigunyazwe yi-FDA.Isebenza ngokuvimbela i-urate transporter, i-URAT1, enesibopho sokumuncwa kabusha kwezinso kwe-uric acid.I-Lesinurad iyi-urate transporter inhibitor yokwelapha i-hyperuricemia ehambisana ne-gout ezigulini ezingazange zifinyelele amazinga e-serum uric acid ehlosiwe nge-xanthine oxidase inhibitor iyodwa.Ithole imvume ye-FDA ngomhla ka-22 Disemba 2015. I-European Commission inikeze isigunyazo sokumaketha esisebenza kuyo yonke i-European Union ngomhla ka-18 February 2016.