I-Lesinurad Intermediate CAS 1533519-84-4 Purity >99.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione

I-CAS: 1533519-84-4

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: I-Off-White Powder

I-Intermediate of Lesinurad (CAS: 878672-00-5)

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione (CAS: 1533519-84-4) ngekhwalithi ephezulu, ephakathi kweLesinurad (CAS: 878672-00-5).I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Lesnurad Intermediates,Please contact: alvin@ruifuchem.com

Lesinurad Intermediates:

Chemical Properties:

Igama Lekhemikhali 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione
Omqondofana 4-(4-Cyclopropylnaphthalen-1-yl) -4H-1,2,4-Triazole-3-Thiol;4-(4-Cyclopropyl-1-Naphthalenyl) -2,4-Dihydro-3H-1,2,4-Triazole-3-Thione;Lesinurad INT3;Lesinurad Ukungcola 20
Isimo Sesitoko Ku-Stock, Commercial Production
Inombolo ye-CAS 1533519-84-4
I-Molecular Formula I-C15H13N3S
Isisindo samangqamuzana 267.35 g/mol
Iphuzu elibilayo 435.2±38.0℃
Ukuminyana 1.41±0.10 g/cm3
I-COA ne-MSDS Iyatholakala
Umsuka Shanghai, China
Isigaba I-Intermediate of Lesinurad (CAS: 878672-00-5)
Ibhrendi I-Ruifu Chemical

Imininingwane:

Izinto Amazinga Wokuhlola Imiphumela
Ukubukeka I-Off-White Powder I-Off-White Powder
Amanzi nguKarl Fischer <0.50% 0.10%
Ukulahlekelwa Ekumisweni <0.50% 0.40%
Izinsalela ekushiseni <0.50% 0.15%
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (HPLC) 99.8%
I-Infrared Spectrum Ihambisana Nesakhiwo Iyahambisana
1H NMR Spectrum Ihambisana Nesakhiwo Iyahambisana
Isiphetho Umkhiqizo uhloliwe futhi uthobelana nemibandela enikeziwe

Iphakheji/Isitoreji/Ukuthumela ngomkhumbi:

Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isiqukathi sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile (2~8℃) nengena umoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.

Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.

Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.

IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.

Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.

Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.

Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.

Isicelo:

I-L-Phenylalanine (H-Phe-OH) (i-CAS: 63-91-2) isetshenziswa njengendawo ephakathi ekuhlanganiseni kweLesinurad (CAS: 878672-00-5).I-Lesinurad iyi-inhibitor ekhethiwe ye-uric acid reabsorption esetshenziswa ngokuhlangana namanye ama-ejenti ekwelapheni i-gout.I-Lesinurad (igama lomkhiqizo i-Zurampic) iyisivimbeli sokuqala esikhethiwe se-uric acid reabsorption (SURI) esigunyazwe yi-FDA.Isebenza ngokuvimbela i-urate transporter, i-URAT1, enesibopho sokumuncwa kabusha kwezinso kwe-uric acid.I-Lesinurad iyi-urate transporter inhibitor yokwelapha i-hyperuricemia ehambisana ne-gout ezigulini ezingazange zifinyelele amazinga e-serum uric acid ehlosiwe nge-xanthine oxidase inhibitor iyodwa.Ithole imvume ye-FDA ngomhla ka-22 Disemba 2015. I-European Commission inikeze isigunyazo sokumaketha esisebenza kuyo yonke i-European Union ngomhla ka-18 February 2016.

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