5-(2R)-2-Oxiranyl-8-Benzyloxy-2(1H)-Quinolinone CAS 173140-90-4 Indacaterol Maleate Intermediate Purity >98.0% (HPLC)
I-Commercial Supply Indacaterol Maleate (CAS: 753498-25-8) Izikhulumi Ezihlobene:
5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS: 312753-53-0
I-8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS: 100331-89-3
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone CAS: 173140-90-4
| Igama Lekhemikhali | 5-(2R)-2-Oxiranyl-8-Benzyloxy-2(1H)-Quinolinone |
| Omqondofana | 8-Benzoxy-5-(R)-Oxiranyl-1H-Quinolin-2-One |
| Inombolo ye-CAS | 173140-90-4 |
| Inombolo yeCAT | I-RF-PI127 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Emakhulwini Amakhilogremu |
| I-Molecular Formula | I-C18H15NO3 |
| Isisindo samangqamuzana | 293.31 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Ephuzi Okuphaphathekile ukuya kokumhlophe |
| Ukuhlanzeka / Indlela Yokuhlaziya | ≥98.0% (HPLC) |
| Umswakama (KF) | ≤1.0% |
| Ukuzungezisa okuqondile | -20.0° ~ -26.0° (C=1 DMF) |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Indacaterol Maleate (CAS: 753498-25-8) Phakathi |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomnikezeli we-5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone (CAS: 173140-90-4) enekhwalithi ephezulu.Kuyinto emaphakathi ngokuvamile ekuhlanganisweni kwe-Indacaterol Maleate (CAS: 753498-25-8).
I-Indacaterol Maleate (CAS: 753498-25-8) iyinhlangano entsha, esebenza isikhathi eside, eqala ngokushesha i-β (2) -adrenoceptor agonist ne-bronchodilator.Isetshenziswa ekwelapheni isifo esingamahlalakhona se-obstructive pulmonary (COPD) kanye nesifuba somoya.I-European Medicines Agency (EMA) igunyaze i-indacaterol njengomuthi ngo-2009 ngaphansi kwegama lokuhweba le-Onbrez ngenkathi e-United States i-Food and Drug Administration yagunyaza ngaphansi kwegama lokuhweba i-Arcapta ngo-2011.Futhi, i-indacaterol iyi-molecule ye-chiral;nokho, i-R-enantiomer ehlanzekile kuphela esatshalaliswa.Kudingeka kuthathwe kanye kuphela ngosuku, ngokungafani nezimbangi ze-formoterol ne-salmeterol.
