I-Posaconazole Intermediate CAS 175712-02-4 Purity >99.0% (GC) Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Posaconazole Intermediate (CAS: 175712-02-4) enekhwalithi ephezulu.I-Ruifu Chemical ihlinzeka ngochungechunge lwezithako zemithi.I-Ruifu inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, amanani amancane nayinqwaba atholakalayo.Thenga i-Posaconazole Emaphakathi,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-Posaconazole Ephakathi |
| Omqondofana | Ukungcola kwe-Posaconazole 21;(5R-Cis)- I-P-Chlorobenzenesulfonic Acid 5;[(3S,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)tetrahydrofuran-3-yl]methyl 4-Chlorobenzenesulfonate;(3S-cis)-4-Chlorobenzenesulfonic Acid [5-(2,4-Difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-Furanyl]methyl Ester |
| Isimo Sesitoko | Kukhona kusitoki |
| Inombolo ye-CAS | 175712-02-4 |
| I-Molecular Formula | I-C20H18ClF2N3O4S |
| Isisindo samangqamuzana | 469.89 g/mol |
| Ukuminyana | 1.49±0.10 g/cm3 |
| Isikhathi Sokugcina. | Indawo epholile neyomile (2~8℃) |
| I-COA ne-MSDS | Iyatholakala |
| Isigaba | Pharmaceutical Intermediates |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | Okuqinile Okumhlophe | Okuqinile Okumhlophe |
| Amanzi nguKarl Fischer | <0.50% | 0.20% |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (GC) | 99.3% |
| 1 H NMR Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| I-LCMS | Ihambisana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nezicaciso | |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni yokugcina impahla epholile neyomile kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Thumela emhlabeni wonke nge-FedEx / DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-Posaconazole Ephakathi (i-CAS: 175712-02-4) iphakathi kwe-Posaconazole (CAS: 171228-49-2).I-Posaconazole, eyethulwe e-UK, iyilungu elisha lesigaba se-azole lama-antifungal agents ukufinyelela emakethe.Ikhonjiswe ekwelapheni nasekuvimbeleni uhla lwezifo zesikhunta ezihlaselayo, okuhlanganisa i-aspergillosis, i-fusariosis, i-chromoblastomycosis, i-mycetoma, ne-coccidiomycosis ezigulini ezingafuni, noma ezingabekezeleli, ukwelashwa okujwayelekile nge-amphotericin B kanye/noma i-itraconazole.E-US, kugunyazwe ukuvimbela izifo ze-Aspergillus kanye ne-Candida ezigulini ezineminyaka engu-13 ubudala ezisengozini enkulu yokuthola lezi zifo ngenxa yokuzivikela komzimba.Ukwengeza, kuvunyelwe ukwelashwa kwe-oropharyngeal candidiasis.I-Posaconazole inomsebenzi owandisiwe ngaphezu kwamanye amalungu e-azole antifungals.Ngaphezu komsebenzi onamandla omelene nezimo eziphikisayo ze-aspergillosis kanye ne-fluconazole-resistant Candida, ibonisa umsebenzi ngokumelene namaZygomycetes.
I-Biochem/Physiol Actions I-Posaconazole iyi-ejenti enamandla kakhulu ye-antifungal ebanzi ngokumelene ne-yeast infection ebangelwa ikakhulukazi i-Candida sp.Ivimbela ukukhula kwesikhunta ngokuvimbela i-enzyme i-lanosterol 14α-demethylase (CYP51).Ngokungafani namanye ama-azole e-antifungal, i-posaconazole kubikwe ukuthi ayiwukhuthazi indlela yepompo ye-efflux.I-Posaconazole ibonisa imiphumela ye-antichagasic ngokumelene nezinhlobo ezahlukene ze-Trypanosoma cruzi ezibangela isifo se-Chagas.
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