I-6,7-Bis(2-Methoxyethoxy)-4(3H)-Quinazolinone CAS 179688-29-0 Erlotinib Hydrochloride Intermediate Purity >99.0% (HPLC)
Umkhiqizi ohamba phambili nomphakeli we-Erlotinib Hydrochloride Intermediates
I-Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | 6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one |
| Omqondofana | 6,7-Bis(2-Methoxyethoxy)-4(3H)-Quinazolinone;I-6,7-Bis (2-Methoxyethoxy) -3,4-Dihydroquinazolin-4-one;I-6,7-Bis(2-Methoxyethoxy) -4-Hydroxyquinazoline;I-6,7-Bis(2-Methoxyethoxy)-4-Quinazolinol;I-CP-380736 |
| Ukungcola | I-Erlotinib Ukungcola A;I-Erlotinib Lactam Ukungcola |
| Inombolo ye-CAS | 179688-29-0 |
| Inombolo yeCAT | RF2685 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C14H18N2O5 |
| Isisindo samangqamuzana | 294.31 |
| I-Melting Point | 190.0 ukuze 194.0 ℃ |
| Ukuminyana | 1.26±0.1 g/cm3 |
| Kuyazwela | Kuyazwela emoyeni |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Emhlophe noma Engamhlophe |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
| I-Melting Point | 190.0 ukuze 194.0 ℃ |
| Ukulahlekelwa Ekumisweni | <0.50% |
| Izinsalela ekushiseni | <0.20% |
| Ukungcola Okuhlobene kwe-HPLC | |
| Ukungcola Ngamunye | <0.50% |
| Ukungcola Okuphelele | <1.00% |
| Izinsimbi Ezisindayo | <10ppm |
| I-Infrared Spectrum | Ivumelana Nesakhiwo |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Intermediate ye-Erlotinib Hydrochloride (CAS: 183319-69-9) |
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Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
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Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
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I-6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one (CAS: 179688-29-0) iphakathi kwe-Erlotinib Hydrochloride (CAS: 183319-69-9).I-Erlotinib Hydrochlorate iyi-molecule encane i-tyrosine kinase inhibitor esebenza ngokuguqukayo kuma-epidermal growth factor receptors, i-hydrochloride ye-erlotinib, umuthi oqondiswe kumangqamuzana.I-US Food and Drug Administration (FDA) igunyaze i-erlotinib (i-Tarceva) ehlanganiswe ne-gemcitabine njengendlela yokwelapha yomugqa wokuqala yomdlavuza we-pancreatic othuthuke kakhulu kanye ne-metastatic.Isetshenziswa kakhulu njengokwelashwa komugqa wesibili noma wesithathu kumdlavuza wamaphaphu othuthukisiwe endaweni noma we-metstatic non-small cell lung (NSCLC) futhi njengokwelapha umdlavuza wamaphaphu.Isetshenziswa njenge-tyrosine inhibitor yokwelashwa kwe-NSCLC.I-compound encane yamangqamuzana i-Erlotinib Hydrochlorate iyi-tyrosine kinase receptor inhibitor evimbela ukwanda kwamangqamuzana e-tumor ngokuvimbela i-phosphorylation, ebophezela kusizinda se-intracellular catalytic se-tyrosine kinase emqhudelwaneni ne-ATP, ngaleyo ndlela ivimbele ukudluliswa kwesignali ephansi kanye nokuvimbela umsebenzi we-tumor cell ligand encike. HER-1/EGFR.
