I-Methyl 2-Acetylamino-3-Chloropropionate CAS 18635-38-6 Ramipril Intermediate Purity ≥99.0% (HPLC)
I-Ruifu Chemical ingumkhiqizi ohamba phambili we-Methyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6) enekhwalithi ephezulu, emaphakathi ye-Ramipril (CAS 87333-19-5).I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Methyl 2-Acetylamino-3-Chloropropionate,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-Methyl 2-Acetylamino-3-Chloropropionate |
| Omqondofana | I-LN-Acetyl-β-Chloroalanine Methyl Ester;I-Methyl (R) -2-Acetamido-3-Chloropropanoate;I-N-Acetylmine-3-Chloro-L-Alaninemethyl Ester;I-Methyl N-Acetyl-3-Chloro-L-Alaninate;I-Methyl N-Acetyl-3-Chloroalaninate;I-Ac-DL-Ala(Cl)-OMe |
| Isimo Sesitoko | Ku-Stock, Commercial Production |
| Inombolo ye-CAS | 18635-38-6 |
| I-Molecular Formula | I-C6H10ClNO3 |
| Isisindo samangqamuzana | 179.60 g/mol |
| I-Melting Point | 102.0~105.0℃ |
| I-COA ne-MSDS | Iyatholakala |
| Umsuka | Shanghai, China |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | Impushana Emhlophe Kuya Kumhlophe | Iyahambisana |
| I-Melting Point | 102.0~105.0℃ | 102.0~105.0℃ |
| Ukulahlekelwa Ekumisweni | ≤0.50% | 0.26% |
| Ukuzungezisa okuqondile | -13.0° ukuze -16.0° | -13.15° |
| Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) | 99.27% |
| I-Infrared Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| 1H NMR Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
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IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
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Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
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I-Methyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6), ephakathi kwe-Ramipril (CAS 87333-19-5).I-Ramiprilat iyi-metabolite esebenzayo ye-ramipril futhi isebenza njenge-angiotensin-converting enzyme inhibitor (pKi = 9.08 enhliziyweni yomuntu) ukuze icindezele ukuguqulwa kwe-angiotensin I ibe yi-angiotensin II kanye nokuwohloka kwe-bradykinin, ngaleyo ndlela kuvimbele i-vasoconstriction.Ngaphezu kwalokho, i-ramiprilat kubikwa ukuthi iphazamisa ukukhonjwa kwe-B2 kinin receptors kuma-endothelial cell membranes futhi kuvimbele ukusayina kwe-bradykinin.Ngaphezu kwemiphumela yayo ye-cardioprotective kuzo zombili izinhlobo zezilwane kanye nezifundo zomtholampilo, i-ramiprilat kubikwe ukuthi ivimbela umsebenzi we-matrix metalloproteinase-3 kanye -9 ku-fistula yesifo sika-Crohn.
