3-Chloro-4-(3-Fluorobenzyloxy)aniline CAS 202197-26-0 Lapatinib Intermediate Purity >98.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: 3-Chloro-4-(3-Fluorobenzyloxy)aniline

I-CAS: 202197-26-0

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Okunsundu kuya kuPhoda Omnyama

Iphakathi kweLapatinib / Lapatinib Ditosylate Monohydrate

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-3-Chloro-4-(3-Fluorobenzyloxy)aniline (CAS: 202197-26-0) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Lapatinib Intermediates,Please contact: alvin@ruifuchem.com

I-Lapatinib Intermediates:

I-Lapatinib Base	I-CAS 231277-92-2
I-Lapatinib Ditosylate Monohydrate	I-CAS 388082-78-8
I-Sodium Methanesulfinate	I-CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	I-CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	I-CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	I-CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	I-CAS 16064-08-7
I-5-Formyl-2-Furanboronic Acid	I-CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	I-CAS 231278-84-5

Chemical Properties:

Igama Lekhemikhali	3-Chloro-4-(3-Fluorobenzyloxy)aniline
Omqondofana	3-Chloro-4-[(3-Fluorophenyl)methoxy]aniline;4-(3-Fluorobenzyloxy) -3-Chlorobenzenamine;I-Lapatinib Intermediate B
Isimo Sesitoko	Ku-Stock, Commercial Production
Inombolo ye-CAS	202197-26-0
I-Molecular Formula	I-C13H11ClFNO
Isisindo samangqamuzana	251.69 g/mol
I-Melting Point	78.0 ukuze 82.0℃
Ukuminyana	1.306±0.06 g/cm3
I-COA ne-MSDS	Iyatholakala
Isampula	Iyatholakala
Umsuka	Shanghai, China
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Izinto	Amazinga Wokuhlola	Imiphumela
Ukubukeka	I-Brown kuya kuPowder Omnyama	Iyahambisana
I-Melting Point	78.0 ukuze 82.0℃	80.7℃
Ukulahlekelwa Ekumisweni	<1.00%	Iyahambisana
Izinsalela ekushiseni	<0.50%	Iyahambisana
Ukungcola Okuhlobene kwe-HPLC	<2.00%	0.64%
Ukuhlanzeka / Indlela Yokuhlaziya	>98.0% (HPLC)	99.36%
1H NMR Spectrum	Ihambisana Nesakhiwo	Iyahambisana
Isiphetho	Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe
Isicelo	Iphakathi kweLapatinib / Lapatinib Ditosylate Monohydrate

Iphakheji/Isitoreji/Ukuthumela ngomkhumbi:

Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.

202197-26-0 - Ulwazi Lokuphepha:

Ama-ID e-UN 3077
I-HS Code 2921420090
I-Hazard Class 9
Ukupakisha Iqembu III

202197-26-0 - Isicelo:

I-3-Chloro-4-(3-Fluorobenzyloxy)aniline (i-CAS: 202197-26-0) iphakathi ekuhlanganiseni kwe-Lapatinib / Lapatinib Ditosylate Monohydrate.
I-Lapatinib iyisidakamizwa esiqondise umdlavuza webele esakhiwe yi-British GlaxoSmithKline Co. Ama-Human ErbB receptors ayingxenye yomndeni wama-receptor we-tyrosine kinase (TK), okuhlanganisa i-ErbB1 (EGFR), ErbB2 (HER2), ErbB3 (HER3), kanye ne-ErbB4 (HER4) .Ama-ErbB-1 (EGFR) kanye ne-ErbB-2 (HER-2) receptors avame ukuvezwa ngokweqile noma ashintshwe ngenye indlela ezigulini ezinomdlavuza.I-Human epidermal growth factor receptor 2 (ErbB-2, HER-2) yaziwa njenge-oncogene yomuntu ehlobene eduze nomdlavuza webele.Ukubonakaliswa kwayo okuphezulu kumdlavuza webele kuvame ukubikezela i-lymph node metastasis kanye nokuhlukaniswa kwesimila okubi, nokubikezela okubi.I-HER-2 ingenye yama-molecule okuhloswe ngawo ukwelapha okuqondene nomdlavuza webele.I-Lapatinib ingenza ngasikhathi sinye kuzo zombili i-Her-1 Her-2.Imiphumela yebhayoloji yale ndlela evimbela ukwanda nokukhula kwamaseli wesimila mikhulu kakhulu kunokusebenza ekuhlosweni okukodwa.Inhlanganisela ye-Lapatinib ne-Capecitabine isetshenziselwa ukwelapha iziguli ezinomdlavuza webele osuthuthukile noma we-metastatic ngokuvezwa ngokweqile kwe-epidermal receptor2 yomuntu, eseselashwe kakade nge-anthracyclines, i-paclitaxel, ne-trastuzumab.Izivivinyo zemitholampilo zibonise ukuthi i-Lapatinib iphinde yelapha ngempumelelo iziguli zomdlavuza wohlobo lwe-HER2 ezinokumelana ne-Herceptin.