I-Lapatinib Intermediate CAS 231278-84-5 Purity >98.0% (HPLC)

Incazelo emfushane:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde

I-CAS: 231278-84-5

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Okuphuzi Okuphaphathekile kuye Kokuphuzi Okuqinile

I-Intermediate of API (CAS 388082-77-7)

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

I-Lapatinib Intermediates:

I-Lapatinib Base	I-CAS 231277-92-2
I-Lapatinib Ditosylate Monohydrate	I-CAS 388082-78-8
I-Sodium Methanesulfinate	I-CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	I-CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	I-CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	I-CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	I-CAS 16064-08-7
I-5-Formyl-2-Furanboronic Acid	I-CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	I-CAS 231278-84-5

Chemical Properties:

Igama Lekhemikhali	5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde
Omqondofana	I-Lapatinib Ephakathi 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde
Inombolo ye-CAS	231278-84-5
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C26H17ClFN3O3
Isisindo samangqamuzana	473.90
I-Melting Point	225.0 ukuze 235.0 ℃
Ukuminyana	1.407±0.06 g/cm3
I-Refractive Index	1.694
I-COA ne-MSDS	Iyatholakala
Umsuka	Shanghai, China
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Eqinile Ephuzi Okuphuzi ukuya Kuphuzi
Ukuhlanzeka / Indlela Yokuhlaziya	>98.0% (HPLC)
I-Melting Point	225.0~235.0℃
Ukulahlekelwa Ekumisweni	<1.00%
Izinsalela Ekushiseni	<0.50%
Ukungcola Okuphelele	<2.00%
Izinsimbi Ezisindayo (njenge-Pb)	<20ppm
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Intermediate of API (CAS 388082-77-7)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

231278-84-5 - Isicelo:

I-5--[4--[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) iphakathi kwe-API (CAS 388082-77-7 ).(i-CAS 388082-77-7) iyisidakamizwa esiqondise umdlavuza webele esakhiwe yi-British GlaxoSmithKline Co. Kuyi-tyrosine kinase inhibitor engavimbela ngempumelelo umsebenzi we-tyrosine kinase we- human epidermal growth factor receptors 1 kanye ne-2 (ErbB1, ErbB2).Ingenza ngokuhlukile ngezindlela ezihlukahlukene, iqinisekise ukuthi amangqamuzana omdlavuza webele awakwazi ukuthola izimpawu zokukhula.Ivimbela i-intracellular EGFR (ErbB-1) kanye ne-HER2 (ErbB-2) amasayithi e-ATP, ivimbela i-tumor cell phosphorylation nokusebenza, ivimbela amasignali okulawula phansi ngokusebenzisa i-homogeneity kanye ne-heterogeneity ye-EGFR (ErbB-1) ne-HER2 (ErbB-1) i-dimerization.