1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one CAS 27387-31-1 Ondansetron HCl Dihydrate Intermediate Purity >99.0% (HPLC)

Incazelo emfushane:

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one

I-CAS: 27387-31-1

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: I-Crystalline Powder Emhlophe noma Engamhlophe

Izithameli ze-Ondansetron Hydrochloride Dihydrate

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Please contact: alvin@ruifuchem.com

Abalamuli Abahlobene:

Abaphakathi Abahlobene Be-Ondansetron Hydrochloride Dihydrate

1,3-Cyclohexanedione	I-CAS 504-02-9
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one	I-CAS 27387-31-1
I-Ondansetron Hydrochloride Dihydrate	I-CAS 103639-04-9

Chemical Properties:

Igama Lekhemikhali	1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one
Omqondofana	I-1,2,3,4-Tetrahydro-9-Methylcarbazol-4-one;1,2,3,4-Tetrahydro-9-Methyl-4-Oxocarbazole
Isimo Sesitoko	Kukhona kusitoki
Ukungcola	I-Ondansetron USP Ehlobene Inhlanganisela C;Ondansetron EP Ukungcola C;I-Ondansetron Hydrochloride Dihydrate Ukungcola C
Inombolo ye-CAS	27387-31-1
I-Molecular Formula	I-C13H13NO
Isisindo samangqamuzana	199.25 g/mol
I-Melting Point	199.0 ukuze 203.0 ℃
Ukuminyana	1.21±0.10 g/cm3
I-COA ne-MSDS	Iyatholakala
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Izinto	Amazinga Wokuhlola	Imiphumela
Ukubukeka	I-Crystalline Powder emhlophe ukuya kokumhlophe	Iyahambisana
I-Melting Point	199.0 ukuze 203.0 ℃	200.0 ukuze 202.0 ℃
Ukungcola Okukodwa	<0.50%	Iyahambisana
Ukungcola Okuphelele	<1.00%	Iyahambisana
Ukuhlanzeka / Indlela Yokuhlaziya	>99.0% (HPLC)	99.65%
1 H NMR Spectrum	Ivumelana Nesakhiwo	Iyahambisana
Isiphetho	Umkhiqizo uhloliwe futhi uthobelana nezicaciso

Iphakheji/Isitoreji/Ukuthumela ngomkhumbi:

Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina esitsheni esivalwe ngci.Gcina endaweni yokugcina impahla epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.

Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.

Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.

IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.

Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.

Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.

Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.

27387-31-1 - Ubungozi Nokuphepha:

Amakhodi Engozi
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
R52/53 - Iyingozi ezintweni eziphila emanzini, ingase ibangele imiphumela emibi yesikhathi eside endaweni yasemanzini.
R25 - Kunobuthi uma ugwinywe
Incazelo Yokuphepha
S22 - Ungaphefumuli uthuli.
I-S24/25 - Gwema ukuthintana nesikhumba namehlo.
I-S61 - Gwema ukudedela imvelo.Bheka imiyalelo ekhethekile / amaphepha edatha okuphepha.
S45 - Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.)
Omazisi be-UN UN 2811 6.1 / PGIII

27387-31-1 - Isicelo:

I-1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) isetshenziswa njengendawo ephakathi ye-Ondansetron Hydrochloride Dihydrate (CAS: 103639-04-9).Ukuthuthukiswa kwenkampani yase-United Kingdom Glaxo, ngo-1990 eFrance, imakethe yase-United Kingdom.Umkhiqizo ungumphikisi we-serotonin (5-HT3) okhetha kakhulu we-serotonin (5-HT3), ungavimbela I-Nausea ebangelwa i-chemotherapy kanye ne-radiotherapy Vomit, enamandla amakhulu kanye nokukhetha okuphezulu, ingalawula amathumbu amancane kanye nama-CTZ receptors okubangelwa ukugqugquzelwa kwe-Vomit.Ilungele ukwelapha I-Nausea Vomit ebangelwa ukwelashwa ngamakhemikhali kanye ne-radiotherapy, futhi ingase isetshenziselwe ukuvimbela nokwelashwa KweNausea Vomit ebangelwa ngemva kokuhlinzwa.

I-Ondansetron, i-granisetron ne-dolasetron izidakamizwa ezintathu ze-antiemetic ezivame ukusetshenziswa emtholampilo, i-ondansetron iyisivimbeli se-5-hydroxytryptamine (5-HT3) esinamandla, esikhethayo futhi esibuyisele emuva se-Alpha 1, Alpha 2, beta 1, Beta 2 adrenergic receptors kanye ne-histamine H1, I-h2 receptor inomphumela omncane, futhi ayinawo umthelela ophikisayo ku-H receptor, i-central and peripheral dopaminergic receptors, futhi inganqanda Isicanucanu Nokuhlanza okubangelwa ukwelapha ngamakhemikhali kanye ne-radiotherapy.Uma kuqhathaniswa ne-metoclopramide, Umphumela we-antiemetic wawunamandla futhi kwakungekho ukusabela kwe-extrapyramidal.I-Cisplatin, i-cyclophosphamide, i-doxorubicin ebangelwa uMphalazo ingakhiqiza umphumela wokulwa nesicanucanu osheshayo futhi onamandla.Ifanele ukwelashwa kwezidakamizwa ze-cytotoxic ezibangelwa ukwelashwa ngamakhemikhali kanye nokwelashwa ngemisebe I-Nausea Vomit, kodwa futhi ukuvimbela nokwelashwa kweNausea Vomit okubangelwa ukuhlinzwa.I-ondansetron isebenza njengesiteshi sokudlulisa phakathi kwezinzwa ze-visceral afferent ezicushiwe emgudwini wamathumbu kanye noMphalazo wezikhungo kumgogodla, okubangela ukunyakaza kwesisu kanye ne-diaphragmatic.Izidakamizwa ze-Chemotherapy kanye nokwelapha ngemisebe kungabangela ukukhululwa kwe-5-HT emathunjini amancane, futhi i-Vomit reflex ibangelwa ukukhuthazwa kwenzwa ye-vagus ngokusebenzisa i-5-HT3 receptor.Lo mkhiqizo uvimba ukwenzeka kwale reflex, kuyilapho uvimba Ukuphalaza okubangelwa isenzo esimaphakathi.Indlela yokwenza yayingaziwa nge-Nausea Vomit ngemva kokuhlinzwa.I-Ondansetron ehlanganiswe ne-dexamethasone ingathuthukisa umphumela we-antiemetic.