I-CAS 274901-16-5 Purity ≥99.0% (HPLC) API
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| Omqondofana | I-LAF-237 |
| Inombolo ye-CAS | 274901-16-5 |
| Inombolo yeCAT | I-RF-API30 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
| I-Molecular Formula | I-C17H25N3O2 |
| Isisindo samangqamuzana | 303.4 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder Emhlophe |
| Ukuhlonza | I-IR, i-HPLC: Kumele Ihambisane Nezinga Lereferensi |
| I-Specific Optical Rotation | -82.0° ukuya ku-92.0° |
| I-Melting Point | 148.0~152.0℃ |
| Ukulahlekelwa Ekumisweni | ≤0.50% |
| Izinsalela ekushiseni | ≤0.10% |
| Izinsimbi Ezisindayo | ≤20ppm |
| I-Sulfate | ≤0.02% |
| I-Chloride | ≤0.05% |
| Ukungcola KweChiral | Ukungcola kwe-R-Isomer ≤0.50% |
| Izincibilikisi Ezisele | |
| I-acetonitrile | ≤410ppm |
| I-Dichloromethane | ≤600ppm |
| Isopropyl Utshwala | ≤5000ppm |
| Ukungcola Okuhlobene | Nge-HPLC |
| Ukungcola A | ≤0.15% |
| Ukungcola B | ≤0.15% |
| Ukungcola C | ≤0.20% |
| Okunye Ukungcola Okukodwa | ≤0.10% |
| Ukungcola Okuphelele | ≤1.00% |
| Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-API, Type 2 Diabetes Mellitus (T2DM) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-API (CAS: 274901-16-5) enekhwalithi ephezulu.I-API (CAS: 274901-16-5)iyi-ejenti yomlomo elwa ne-hyperglycemic (isidakamizwa esilwa nesifo sikashukela) yesigaba esisha se-dipeptidyl peptidase-4 (DPP-4) inhibitor.Yasungulwa ngabakwaNovartis (Novartis) Pharmaceutical Co., Ltd, kungenye inhibitor elawulwa ngomlomo ye-Dipeptidyl peptidase-IV.Ngo-2008, kugunyazwe ukumakethwa e-European Union yokwelashwa kwesifo sikashukela sohlobo 2.I-API (i-CAS: 274901-16-5) ivimbela ukwenziwa kusebenze kwe-GLP-1 ne-GIP nge-DPP-4, ivumela i-GLP-1 ne-GIP ukuthi iqinise ukukhiqizwa kwe-insulin kumaseli e-beta futhi icindezele ukukhululwa kwe-glucagon ngamaseli e-alpha Iziqhingi zeLangerhans ku-pancreas.I-API (CAS: 274901-16-5) ikhonjiswe ukunciphisa i-hyperglycemia kuhlobo lwe-2 yesifo sikashukela.
