I-CAS 361440-67-7 Purity >98.5% (HPLC) Factory

Incazelo emfushane:

(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester

I-CAS: 361440-67-7

Ubumsulwa: >98.5% (HPLC)

Ukubukeka: Impushana Emhlophe

I-Intermediate of API (CAS: 361442-04-8)

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester
Omqondofana I-N-Boc-L-cis-4,5-Methanoprolineamide;I-N-Boc-cis-4,5-Methano-L-Prolinamide;I-tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate
Inombolo ye-CAS 361440-67-7
Inombolo yeCAT I-RF-PI1990
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C11H18N2O3
Isisindo samangqamuzana 226.27
Iphuzu elibilayo 388.9±21.0℃
Ukuminyana 1.228
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Emhlophe
Ukuhlanzeka / Indlela Yokuhlaziya >98.5% (HPLC)
Ukulahlekelwa Ekumisweni <0.50%
Izinsalela ekushiseni <0.20%
Ukungcola Ngamunye <1.00%
Ukungcola Okuphelele <1.50%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate of API (CAS: 361442-04-8)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) iyi-intermediate ye-API (CAS: 361442 -04-8).(I-CAS: 361442-04-8) i-hypoglycemic yomlomo (isidakamizwa esilwa nesifo sikashukela) sekilasi le-dipeptidyl peptidase-4 (DPP-4) inhibitor yezidakamizwa.Ukuthuthukiswa kwangaphambi kwesikhathi kwaba yiBristol-Myers Squibb kuphela;ngo-2007 i-AstraZeneca yajoyina i-Bristol-Myers Squibb ukuze ithuthukise inhlanganisela yokugcina futhi ihlanganyele ekukhangiseni komuthi.NgoJuni 2008, kwamenyezelwa ukuthi i-Onglyza kuzoba igama lokuhweba okuzomakethwa ngalo.I-API (CAS: 361442-04-8) isetshenziswa njenge-monotherapy noma ngokuhlanganiswa nezinye izidakamizwa ekwelapheni uhlobo 2 lwesifo sikashukela.Imuncwa ngokushesha ngemuva kokuphathwa ngomlomo futhi inephrofayili ye-pharmacokinetic ehambisana nomthamo kanye ngosuku.Idlala indima ngokuvimbela ukuwohloka kwe-GLP-l.I-GLP-I amahomoni akhiqizwa ngokwemvelo emathunjini ngemva kokudla ukudla.

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