I-CAS 361440-67-7 Purity >98.5% (HPLC) Factory
I-Ruifu Chemical Supply Related Intermediate
I-CAS 361442-04-8
I-CAS 945667-22-1
(R)-1-Boc-3-Aminopiperidine CAS 188111-79-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
I-Boc-3-Hydroxy-1-Adamantyl-D-Glycine CAS 361442-00-4
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid CAS 709031-28-7
Igama Lekhemikhali | (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester |
Omqondofana | I-N-Boc-L-cis-4,5-Methanoprolineamide;I-N-Boc-cis-4,5-Methano-L-Prolinamide;I-tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate |
Inombolo ye-CAS | 361440-67-7 |
Inombolo yeCAT | I-RF-PI1990 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C11H18N2O3 |
Isisindo samangqamuzana | 226.27 |
Iphuzu elibilayo | 388.9±21.0℃ |
Ukuminyana | 1.228 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe |
Ukuhlanzeka / Indlela Yokuhlaziya | >98.5% (HPLC) |
Ukulahlekelwa Ekumisweni | <0.50% |
Izinsalela ekushiseni | <0.20% |
Ukungcola Ngamunye | <1.00% |
Ukungcola Okuphelele | <1.50% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate of API (CAS: 361442-04-8) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) iyi-intermediate ye-API (CAS: 361442 -04-8).(I-CAS: 361442-04-8) i-hypoglycemic yomlomo (isidakamizwa esilwa nesifo sikashukela) sekilasi le-dipeptidyl peptidase-4 (DPP-4) inhibitor yezidakamizwa.Ukuthuthukiswa kwangaphambi kwesikhathi kwaba yiBristol-Myers Squibb kuphela;ngo-2007 i-AstraZeneca yajoyina i-Bristol-Myers Squibb ukuze ithuthukise inhlanganisela yokugcina futhi ihlanganyele ekukhangiseni komuthi.NgoJuni 2008, kwamenyezelwa ukuthi i-Onglyza kuzoba igama lokuhweba okuzomakethwa ngalo.I-API (CAS: 361442-04-8) isetshenziswa njenge-monotherapy noma ngokuhlanganiswa nezinye izidakamizwa ekwelapheni uhlobo 2 lwesifo sikashukela.Imuncwa ngokushesha ngemuva kokuphathwa ngomlomo futhi inephrofayili ye-pharmacokinetic ehambisana nomthamo kanye ngosuku.Idlala indima ngokuvimbela ukuwohloka kwe-GLP-l.I-GLP-I amahomoni akhiqizwa ngokwemvelo emathunjini ngemva kokudla ukudla.