I-Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Purity >99.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: Lapatinib Ditosylate Monohydrate

I-CAS: 388082-78-8

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: Okuphuzi Okuphaphathekile ukuya Kokuphuzi I-Crystalline Powder

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

I-Lapatinib Intermediates:

I-Lapatinib Base	I-CAS 231277-92-2
I-Lapatinib Ditosylate Monohydrate	I-CAS 388082-78-8
I-Sodium Methanesulfinate	I-CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	I-CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	I-CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	I-CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	I-CAS 16064-08-7
I-5-Formyl-2-Furanboronic Acid	I-CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	I-CAS 231278-84-5

Chemical Properties:

Igama Lekhemikhali	I-Lapatinib Ditosylate Monohydrate
Omqondofana	N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Inombolo ye-CAS	388082-78-8
Isimo Sesitoko	Kukhona kusitoki
I-Molecular Formula	C29H26ClFN4O4S·2(C7H8O3S)·H2O
Isisindo samangqamuzana	943.48
I-COA ne-MSDS	Iyatholakala
Umsuka	Shanghai, China
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Eyikristalu Ephuzi Ephuzi ukuya Ephuzi
Ukuhlanzeka / Indlela Yokuhlaziya	≥99.0% (HPLC)
I-Melting Point	240.0~242.0℃
Umswakama (KF)	1.9~2.4%
Ukungcola Okukodwa	≤0.50%
Ukungcola Okuphelele	≤1.00%
Izinsimbi Ezisindayo (njenge-Pb)	≤20ppm
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-API;Ezokwelapha iziguli ezinomdlavuza webele

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

388082-78-8 - Isicelo:

I-Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) iwusawoti we-ditosylate weI-CAS 231277-92-2, i-quinazoline yokwenziwa, esebenza ngomlomo enekhono lomsebenzi we-antineoplastic.Ivimbela ngokubuyisela i-phosphorylation ye-epidermal growth factor receptor (EGFR), ErbB2, kanye ne-Erk-1 ne-2 kanye ne-AKT kinases;iphinde ivimbele amazinga amaprotheni e-cyclin D emigqeni yeseli yesimila somuntu kanye nama-xenografts.I-EGFR kanye ne-ErbB2 iye yathinteka ekukhuleni kwezinhlobo ezihlukahlukene zesimila.Yethulwa ukuze kwelashwe umdlavuza webele osezingeni eliphezulu noma we-metastatic HER2 (ErbB2) kwabesifazane abathole ukwelashwa kwangaphambili.Umuthi watholwa futhi wathuthukiswa yi-GlaxoSmithKline.